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Review
. 2018 May 20;21(5):413-418.
doi: 10.3779/j.issn.1009-3419.2018.05.10.

[Stereotactic Body Radiotherapy for Centrally Located Non-small Cell Lung Cancer]

[Article in Chinese]
Yuming Wan  1 , Jing Huang  2 , Feng Xu  1
Affiliations
Review

[Stereotactic Body Radiotherapy for Centrally Located Non-small Cell Lung Cancer]

[Article in Chinese]
Yuming Wan et al. Zhongguo Fei Ai Za Zhi. .

Abstract
in English, Chinese

A few study has proven that about 90% of local control rates might be benefit from stereotactic body radiotherapy (SBRT) for patients with medically inoperable stage I non-small cell lung cancer (NSCLC), it is reported SBRT associated overall survival and tumor specific survival is comparable with those treated with surgery. SBRT has been accepted as the first line treatment for inoperable patients with peripheral located stage I NSCLC. However, the role of SBRT in centrally located lesions is controversial for potential toxic effects from the adjacent anatomical structure. This paper will review the definition, indication, dose regimens, dose-volume constraints for organs at risk, radiation technology, treatment side effect of centrally located NSCLC treated with SBRT and stereotactic body proton therapy.

【中文题目：中央型非小细胞肺癌立体定向放射治疗】 【中文摘要：已有的少数研究表明，早期不可手术非小细胞肺癌立体定向放射治疗肿瘤局控率可超过90%，患者中位生存时间和总生存率接近外科手术治疗。近年来立体定向放射治疗已成为I期不可手术周围型非小细胞肺癌患者的推荐治疗。但中央型肺癌因其解剖位置多毗邻纵隔内重要脏器，常可伴有更明显的放疗副反应。中央型肺癌是否能进行立体定向放射治疗目前尚无统一定论，本文主要对中央型非小细胞肺癌立体定向放射治疗的定义、适应症、剂量分割方式、危及器官剂量-体积限制、放疗技术支持、副反应及立体定向质子治疗进行综述。 】 【中文关键词：立体定向放射治疗；中央型；肺肿瘤】.

Keywords: Centrally; Lung neoplasms; Stereotactic body radiotherapy.

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References

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