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Case Reports
. 2018 Apr;14(1):151-154.
doi: 10.5152/iao.2018.3609.

Giant Cell Tumor of the Temporal Bone and Skull Base: A Case Report

İsa Kaya  1 , Murat Benzer  1 , Göksel Turhal  2 , Gode Sercan  1 , Cem Bilgen  1 , Tayfun Kirazlı  1
Affiliations
Case Reports

Giant Cell Tumor of the Temporal Bone and Skull Base: A Case Report

İsa Kaya et al. J Int Adv Otol. 2018 Apr.

Abstract

Giant cell tumor (GCT) is a benign tumor that originates from undifferentiated mesenchymal cells of the bone marrow. The cranium as well as temporal bone is a rare location for GCTs. Despite its benign nature, GCT may be locally aggressive and has the potential to recur locally. Furthermore, GCT may give rise to pulmonary metastases (~1%) in addition to causing local bone destruction. Surgical excision is the treatment of choice for patients with GCT. We describe the case of a 56-year-old female who presented with headache and hearing loss with extensive GCT, which originated in the squamous part of the temporal bone and extended into the left mandibular fossa and middle ear. She was treated by total resection of the tumor using left temporal craniotomy approach. In this article, we present a case of temporal bone GCT with its clinical features as well as a review of the related literature.

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Conflict of interest statement

Conflict of Interest: No conflict of interest was declared by the authors.

Figures

Figure 1
Figure 1
MRI shows an extensive soft-tissue lesion extending to the mandibular fossa with near-total destruction of the temporal bone (arrow shows tissue lesion in postcontrast T1-weighted MR images).
Figure 2
Figure 2
MRI shows an extensive soft-tissue lesion extending to the mandibular fossa with near-total destruction of the temporal bone (arrow shows tissue lesion in postcontrast T1-weighted MR images).
Figure 3
Figure 3
MRI shows that no residual mass or recurrence was detected.
Figure 4
Figure 4
MRI shows that no residual mass or recurrence was detected.
See this image and copyright information in PMC

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