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. 1988 Nov;51(11):1441-4.
doi: 10.1136/jnnp.51.11.1441.

Inhibition of vasopressin secretion during migraine

C J Poole  1 , S L Lightman
Affiliations

Inhibition of vasopressin secretion during migraine

C J Poole et al. J Neurol Neurosurg Psychiatry. 1988 Nov.

Abstract

Six subjects with a history of increased urinary frequency during migraine were studied. In each case there was a marked diuresis and natriuresis within 12 hours of onset of the headache. This was associated with a significant fall in urinary arginine vasopressin (AVP) (p less than 0.01). Migraine may be associated with altered hypothalamic activity resulting in reduced AVP secretion.

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