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. 2018 Mar-Apr;51(2):234-236.
doi: 10.1590/0037-8682-0298-2017.

The role of the Xpert MTB/RIF assay among adolescents suspected of pulmonary tuberculosis in Rio de Janeiro, Brazil

Thania Luiza de Andrade Sieiro  1 , Rafaela Baroni Aurílio  2 , Elizabeth Cristina C Soares  3 , Silvia S Chiang  4 , Clemax Couto Sant Anna  5   6
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Free article

The role of the Xpert MTB/RIF assay among adolescents suspected of pulmonary tuberculosis in Rio de Janeiro, Brazil

Thania Luiza de Andrade Sieiro et al. Rev Soc Bras Med Trop. 2018 Mar-Apr.
Free article

Abstract

Introduction: The teste rápido molecular para tuberculose (TRM-TB) was introduced in 2014 in Brazil for tuberculosis screening. However, its role in adolescents in Brazil has not been studied.

Methods: A descriptive study of adolescents with suspected tuberculosis using National Laboratory software.

Results: Of 852 (15.4%) suspected cases, 131 were positive by TRM-TB and 2% were resistant to rifampicin. Among TRM-TB-positive cases, 105 (91.4%) were culture-positive. Sixty-four of 96 samples were sensitive to rifampicin by TRM-TB; 11 were resistant to other drugs by drug sensitivity test (DST).

Conclusions: Among suspected cases, 16% were diagnosed by TRM-TB, of which 17% were drug-resistant by DST.

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