[HPV type determination and clinical characteristics in juvenile onset recurrent respiratory papillomatosis]
- PMID: 29771024
- DOI: 10.13201/j.issn.1001-1781.2016.09.015
[HPV type determination and clinical characteristics in juvenile onset recurrent respiratory papillomatosis]
Abstract
Objective:To investigate the relationship between different subtypes of human papillomavirus(HPV) infection and clinical features in juvenile onset recurrent respiratory papillomatosis(JORRP) patients. Method:Two hundred and forty cases with JORRP from 2010 to 2014 were retrospectively analyzed. HPV tpye were determined using tumor specimens taken from surgery, and all patients were divided into different groups based on HPV type. Clinical characteristics of patients from each groups were analyzed. Result:Except for HPV11 single infection or HPV6 single infection, some HPV11 and 6 co-infections were found in children with JORRP. Compared with patients with HPV6 single infection, HPV11 positive patients present an earlier age of onset, more times of operation and higher derkay score during surgery.Conclusion:JORRP in patients infected with HPV11 is more severe than that in patients with HPV6 infection in children.
Keywords: children; human papillomavirus; respiratory tract neoplasms.
Copyright© by the Editorial Department of Journal of Clinical Otorhinolaryngology Head and Neck Surgery.
Conflict of interest statement
The authors of this article and the planning committee members and staff have no relevant financial relationships with commercial interests to disclose.
Similar articles
-
Transcriptomic Landscape of Gene Expression Profiles and Pathways in Juvenile-Onset Recurrent Respiratory Papillomatosis Tumor Tissues and Human Papillomavirus 6 and 11 E6- and E7-Overexpressing Head and Neck Squamous Cell Carcinoma Cell Lines.J Virol. 2022 Jan 26;96(2):e0134221. doi: 10.1128/JVI.01342-21. Epub 2021 Oct 20. J Virol. 2022. PMID: 34669519 Free PMC article.
-
Clinical course of recurrent respiratory papillomatosis: comparison between aggressiveness of human papillomavirus-6 and human papillomavirus-11.Head Neck. 2015 Nov;37(11):1625-32. doi: 10.1002/hed.23808. Epub 2014 Sep 12. Head Neck. 2015. PMID: 24955561
-
[Detection of human papillomavirus in the upper respiratory tract in children without recurrent respiratory papillomatosis].Zhonghua Er Bi Yan Hou Tou Jing Wai Ke Za Zhi. 2012 Dec;47(12):974-7. Zhonghua Er Bi Yan Hou Tou Jing Wai Ke Za Zhi. 2012. PMID: 23328034 Chinese.
-
The role of HPV type in Recurrent Respiratory Papillomatosis.Int J Pediatr Otorhinolaryngol. 2010 Jan;74(1):7-14. doi: 10.1016/j.ijporl.2009.09.004. Epub 2009 Oct 1. Int J Pediatr Otorhinolaryngol. 2010. PMID: 19800138 Review.
-
Annual disease burden due to human papillomavirus (HPV) 6 and 11 infections in Finland.Scand J Infect Dis Suppl. 2009;107:3-32. doi: 10.1080/00365540902887730. Scand J Infect Dis Suppl. 2009. PMID: 19408160 Review.