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doi: 10.1016/j.molcel.2018.05.004.
Forms and Phases in Huntingtin Protein Aggregation
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- PMID: 29775574
- DOI: 10.1016/j.molcel.2018.05.004
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Forms and Phases in Huntingtin Protein Aggregation
Mol Cell.
.
Free article
Abstract
Using a combination of fluorescence microscopy and electron tomography, Peskett et al. (2018), in this issue of Molecular Cell, explore the nucleation of amyloid-like filaments from liquid-like condensates of huntingtin protein exon1 with disease-related polyQ extensions.
Copyright © 2018 Elsevier Inc. All rights reserved.
Comment on
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A Liquid to Solid Phase Transition Underlying Pathological Huntingtin Exon1 Aggregation.Mol Cell. 2018 May 17;70(4):588-601.e6. doi: 10.1016/j.molcel.2018.04.007. Epub 2018 May 10. Mol Cell. 2018. PMID: 29754822 Free PMC article.
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