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Comment
. 2018 May 17;70(4):568-571.
doi: 10.1016/j.molcel.2018.05.006.

At Long Last, a C-Terminal Bookend for the Ubiquitin Code

Andrew Chatr-Aryamontri  1 , Almer van der Sloot  1 , Mike Tyers  2
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At Long Last, a C-Terminal Bookend for the Ubiquitin Code

Andrew Chatr-Aryamontri et al. Mol Cell. .
Free article

Abstract

The ubiquitin-proteasome system controls the stability of myriad protein substrates via short sequence motifs called degrons. Studies by Koren et al. (2018) and Lin et al. (2018) have uncovered a broad new class of degrons located at the extreme C terminus of substrates.

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