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Review
. 2018 Jun;38(2):253-276.
doi: 10.1016/j.cll.2018.02.004.

Diagnostic Molecular Microbiology: A 2018 Snapshot

Marilynn Ransom Fairfax  1 , Martin H Bluth  2 , Hossein Salimnia  3
Affiliations
Review

Diagnostic Molecular Microbiology: A 2018 Snapshot

Marilynn Ransom Fairfax et al. Clin Lab Med. 2018 Jun.

Abstract

Molecular biological techniques have evolved expeditiously and in turn have been applied to the detection of infectious disease. Maturation of these technologies and their coupling with related technological advancement in fluorescence, electronics, digitization, nanodynamics, and sensors among others have afforded clinical medicine additional tools toward expedient identification of infectious organisms at concentrations and sensitivities previously unattainable. These advancements have been adapted in select settings toward addressing clinical demands for more timely and effective patient management.

Keywords: MALDI-TOF; Molecular microbiology; Next gen sequencing; Nuclear magnetic resonance; PCR; Probe tests; Rapid molecular diagnosis of infections; Time lapsed imaging.

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