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Comment
. 2018 Jun 6;26(6):1399-1400.
doi: 10.1016/j.ymthe.2018.05.008. Epub 2018 May 18.

Potential Therapeutic Impact of miR-145 Deregulation in Colorectal Cancer

Ion Cristóbal  1 , Marta Sanz-Alvarez  2 , Blanca Torrejón  3 , Andrea Santos  3 , Melani Luque  2 , Federico Rojo  2 , Jesús García-Foncillas  4
Affiliations
Comment

Potential Therapeutic Impact of miR-145 Deregulation in Colorectal Cancer

Ion Cristóbal et al. Mol Ther. .
No abstract available

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References

    1. Zhu Y., Wang C., Becker S.A., Hurst K., Nogueira L.M., Findlay V.J., Camp E.R. miR-145 Antagonizes SNAI1-Mediated Stemness and Radiation Resistance in Colorectal Cancer. Mol. Ther. 2018;26:744–754. - PMC - PubMed
    1. Drebber U., Lay M., Wedemeyer I., Vallböhmer D., Bollschweiler E., Brabender J., Mönig S.P., Hölscher A.H., Dienes H.P., Odenthal M. Altered levels of the onco-microRNA 21 and the tumor-supressor microRNAs 143 and 145 in advanced rectal cancer indicate successful neoadjuvant chemoradiotherapy. Int. J. Oncol. 2011;39:409–415. - PubMed
    1. Mezencev R., Matyunina L.V., Jabbari N., McDonald J.F. Snail-induced epithelial-to-mesenchymal transition of MCF-7 breast cancer cells: systems analysis of molecular changes and their effect on radiation and drug sensitivity. BMC Cancer. 2016;16:236. - PMC - PubMed
    1. Kent O.A., Fox-Talbot K., Halushka M.K. RREB1 repressed miR-143/145 modulates KRAS signaling through downregulation of multiple targets. Oncogene. 2013;32:2576–2585. - PMC - PubMed
    1. Yang P., Yang Y., An W., Xu J., Zhang G., Jie J., Zhang Q. The long noncoding RNA-ROR promotes the resistance of radiotherapy for human colorectal cancer cells by targeting the p53/miR-145 pathway. J. Gastroenterol. Hepatol. 2017;32:837–845. - PubMed