Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2018 Mar;479(1):62-65.
doi: 10.1134/S1607672918020023. Epub 2018 May 19.

MNT Optimization for Intracellular Delivery of Antibody Fragments

A V Ulasov  1 , Y V Khramtsov  1 , T N Lupanova  1 , A D Tsvetkova  1   2 , A A Rosenkranz  1   2 , T A Slastnikova  1 , G P Georgiev  1 , A S Sobolev  3   4
Affiliations

MNT Optimization for Intracellular Delivery of Antibody Fragments

A V Ulasov et al. Dokl Biochem Biophys. 2018 Mar.

Abstract

We studied the possibility of optimizing modular nanotransporters (MNTs) for the intracellular delivery of antibody fragments into the nuclei of cells of a specified type. Basic MNT with a reduced size retaining the desired functions was obtained, and the principal possibility of obtaining an MNT carrying an antibody fragment by microbiological synthesis was shown.

PubMed Disclaimer

Similar articles

See all similar articles

Cited by

References

    1. J Control Release. 2008 Jun 24;128(3):241-7 - PubMed
    1. Cancer Res. 2006 Nov 1;66(21):10534-40 - PubMed
    1. Biotechnol Prog. 2000 Jul-Aug;16(4):557-63 - PubMed
    1. Cancer Genomics Proteomics. 2013 Nov-Dec;10(6):239-50 - PubMed
    1. Int J Nanomedicine. 2017 Jan 10;12 :395-410 - PubMed

MeSH terms

LinkOut - more resources