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. 2018;26(3):247-259.
doi: 10.1007/s10389-017-0869-1. Epub 2017 Nov 22.

The intention to use HIV-pre-exposure prophylaxis (PrEP) among men who have sex with men in Switzerland: testing an extended explanatory model drawing on the unified theory of acceptance and use of technology (UTAUT)

Sibylle Nideröst  1 , Daniel Gredig  1 , Benedikt Hassler  1 , Franziska Uggowitzer  1 , Patrick Weber  1
Affiliations

The intention to use HIV-pre-exposure prophylaxis (PrEP) among men who have sex with men in Switzerland: testing an extended explanatory model drawing on the unified theory of acceptance and use of technology (UTAUT)

Sibylle Nideröst et al. Z Gesundh Wiss. 2018.

Abstract

Aim: The aim of this study was to determine the intention to use pre-exposure prophylaxis (PrEP) when available and to identify predictors of the intention to use PrEP among men who have sex with men (MSM) living in Switzerland. The theoretical model drew on the Unified Theory of Acceptance and Use of Technology and considered additional variables related specifically to PrEP, HIV protection and the resources of MSM.

Subject and methods: For data collection, we used an anonymous, standardized self-administered online questionnaire. In 2015, we gathered a convenience sample of 556 HIV-negative MSM living in Switzerland. We analyzed the data using descriptive and bivariate statistics and used structural equation modeling to test the hypothesized model.

Results: Predictors of respondents' moderate intention to use PrEP were performance expectancy, effort expectancy, perceived social influence, concerns about using PrEP, attitudes toward condom use, negative experiences of condom use and age. These variables were predicted by HIV protection-related aspects and resources.

Conclusion: The findings provide insights into the complex dynamic underlying the intention to use PrEP.

Keywords: Acceptability; HIV/AIDS; Men having sex with men (MSM); Pre-exposure prophylaxis (PrEP); Switzerland; Unified theory of acceptance and use of technology.

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Conflict of interest statement

Compliance with ethical standardsThis study was fully evaluated and approved by the Swiss National Science Foundation. It did not have to be submitted to an additional formal external ethics committee. All procedures performed in studies involving human participants were in accordance with the ethical standards of the Swiss National Science Foundation and with the 1964 Helsinki Declaration and its later amendments or comparable ethical standards.Informed consent was obtained from all individual participants included in the study.The authors declare that they have no conflict of interest. The main granting institution is an independent foundation. The company producing the substance that plays a central role in the issue under investigation neither motivated this study nor was it involved in the elaboration of the study protocol or the course of investigation. There were also no conflicting loyalties. A representative of the company was consulted to phrase the brief product description used in the course of the questionnaire.

Figures

Fig. 1
Fig. 1
The hypothetical model explaining the intention to use PrEP in MSM
Fig. 2
Fig. 2
Visualization of the results of structural equation modeling. Note: N = 556; method: generalized least squares estimates; GFI = 0.986, AGFI = 0.968, PGFI = 0.423; X2 = 54.045, p = 0.167; CMIN/df = 1.21; SRMR = 0.0359; adj. R2 = 0.50. Non-significant standardized coefficients (p > 0.050) and correlations among the predictors are not illustrated
See this image and copyright information in PMC

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