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Editorial
. 2018 Apr;7(Suppl 2):S95-S99.
doi: 10.21037/tlcr.2018.02.08.

Companion and complementary diagnostics for first-line immune checkpoint inhibitor treatment in non-small cell lung cancer

Jan Trøst Jørgensen  1 , Karsten Bork Nielsen  1
Affiliations
Editorial

Companion and complementary diagnostics for first-line immune checkpoint inhibitor treatment in non-small cell lung cancer

Jan Trøst Jørgensen et al. Transl Lung Cancer Res. 2018 Apr.
No abstract available

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Conflict of interest statement

Conflicts of Interest: JT Jørgensen has worked as a consultant for Agilent, Euro Diagnostica, Oncology Venture and Azanta and has given lectures at meetings sponsored by AstraZeneca, Merck Sharp & Dohme, and Roche. KB Nielsen is a former employee of Agilent.

Comment on

  • First-Line Nivolumab in Stage IV or Recurrent Non-Small-Cell Lung Cancer.
    Carbone DP, Reck M, Paz-Ares L, Creelan B, Horn L, Steins M, Felip E, van den Heuvel MM, Ciuleanu TE, Badin F, Ready N, Hiltermann TJN, Nair S, Juergens R, Peters S, Minenza E, Wrangle JM, Rodriguez-Abreu D, Borghaei H, Blumenschein GR Jr, Villaruz LC, Havel L, Krejci J, Corral Jaime J, Chang H, Geese WJ, Bhagavatheeswaran P, Chen AC, Socinski MA; CheckMate 026 Investigators. Carbone DP, et al. N Engl J Med. 2017 Jun 22;376(25):2415-2426. doi: 10.1056/NEJMoa1613493. N Engl J Med. 2017. PMID: 28636851 Free PMC article.

References

    1. Hersom M, Jørgensen JT. Companion and Complementary Diagnostics-Focus on PD-L1 Expression Assays for PD-1/PD-L1 Checkpoint Inhibitors in NSCLC. Ther Drug Monit 2018;40:9-16. - PubMed
    1. Borghaei H, Paz-Ares L, Horn L, et al. Nivolumab versus Docetaxel in Advanced Nonsquamous Non-Small-Cell Lung Cancer. N Engl J Med 2015;373:1627-39. 10.1056/NEJMoa1507643 - DOI - PMC - PubMed
    1. Brahmer J, Reckamp KL, Baas P, et al. Nivolumab versus Docetaxel in Advanced Squamous-Cell Non-Small-Cell Lung Cancer. N Engl J Med 2015;373:123-35. 10.1056/NEJMoa1504627 - DOI - PMC - PubMed
    1. Herbst RS, Baas P, Kim DW, et al. Pembrolizumab versus docetaxel for previously treated, PD-L1-positive, advanced non-small-cell lung cancer (KEYNOTE-010): a randomised controlled trial. Lancet 2016;387:1540-50. 10.1016/S0140-6736(15)01281-7 - DOI - PubMed
    1. Fehrenbacher L, Spira A, Ballinger M, et al. Atezolizumab versus docetaxel for patients with previously treated non-small-cell lung cancer (POPLAR): a multicentre, open-label, phase 2 randomised controlled trial. Lancet 2016;387:1837-46. 10.1016/S0140-6736(16)00587-0 - DOI - PubMed

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