Sections

• Preface
• I. Basic Research for Innovative Medicine
  • Diverting Glycolysis to Combat Oxidative Stress
  • Metabolic Regulation by Nuclear Receptors
  • Fighting Fire with Fire in Cancer
  • Linear Polyubiquitination: A Crucial Regulator of NF-κB Activation
  • VCP, a Major ATPase in the Cells, as a Novel Drug Target for Currently Incurable Disorders
  • Roles of E-cadherin in Hepatocarcinogenesis
  • The Hippo Signaling Pathway: A Candidate New Drug Target for Malignant Tumors
  • Inhibitory Immunoreceptors on Mast Cells in Allergy and Inflammation
  • Doxycycline-Inducible Autoimmune Blistering Skin Disease Model
  • T Cell Senescence and Autoimmunity
• II. Translational Research for Innovative Medicine
  • IL-6: A New Era for the Treatment of Autoimmune Inflammatory Diseases
  • Pathogenesis of Non-alcoholic Steatohepatitis and Its Potential Therapeutic Strategies
  • Multifaceted Translational Approach to Major Mental Illness
  • Translational Research of Leptin in Lipodystrophy and Its Related Diseases
  • Translational Research of the Activation of the C-Type Natriuretic Peptide (CNP)-Guanylyl Cyclase-B Pathway for Skeletal Dysplasia
  • Clarity and Challenges in Tissue Fibrosis
  • TRP Channels: Their Function and Potentiality as Drug Targets
  • Autophagic Cell Death and Cancer Chemotherapeutics
  • Adrenomedullin as a Potential Therapeutic Agent for Refractory Ulcerative Colitis
  • RNA Activation
• III. New Technology for Innovative Medicine
  • Proceedings of the Uehara Memorial Foundation. Innovative Medicine: Basic Research and Development. Cardiac Reprogramming for Heart Repair
  • Development of a New In Vivo Optical Probe for Biological Diagnosis and Therapy
  • Introduction of Mesenchymal Stem Cells for Liver Surgery (Hepatectomy and Transplantation)
  • Synaptic and Axonal Plasticity Induction in the Human Cerebral Cortex
  • TIM-3 Is a Novel Therapeutic Target for Eradicating Acute Myelogenous Leukemia Stem Cells
  • TGF-β LAP Degradation Products, a Novel Biomarker and Promising Therapeutic Target for Liver Fibrogenesis
  • Cell-Based Regenerative Therapy for Liver Disease