The Incredible Shrinking Spindle
- PMID: 29787705
- DOI: 10.1016/j.devcel.2018.05.007
The Incredible Shrinking Spindle
Abstract
As cell size decreases during the reductive divisions of early development, intracellular structures must shrink to fit. In this issue of Developmental Cell, Lacroix et al. (2018) identify a conserved mechanism of spindle scaling in nematode and sea urchin embryos whereby spindle microtubule polymerization rates decrease as development proceeds.
Copyright © 2018 Elsevier Inc. All rights reserved.
Comment on
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Microtubule Dynamics Scale with Cell Size to Set Spindle Length and Assembly Timing.Dev Cell. 2018 May 21;45(4):496-511.e6. doi: 10.1016/j.devcel.2018.04.022. Dev Cell. 2018. PMID: 29787710 Free PMC article.
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