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. 2018 Aug 1:306:92-93.
doi: 10.1016/j.jneumeth.2018.05.013. Epub 2018 May 19.

Intraepidermal nerve fibres are not the exclusive tranducers of nociception

Matthieu Talagas  1 , Nicolas Lebonvallet  2 , Laurent Misery  3
Affiliations

Intraepidermal nerve fibres are not the exclusive tranducers of nociception

Matthieu Talagas et al. J Neurosci Methods. .

Abstract

The goal of this article is to provide an insight of the most recent data on cutaneous nociception. Indeed recent studies have demonstrated that keratinocytes closely participate in sensory transduction, and therefore, intraepidermal free nerve endings are not exclusive transducers of pain. Therefore, the results of neurophysiological studies should be interpreted in the light of this information.

Keywords: Electrodes; Free nerve endings; Keratinocytes; Pain; Stimulation.

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