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Meta-Analysis
. 2018 Oct 15;67(9):1434-1436.
doi: 10.1093/cid/ciy401.

Polyspecific Intravenous Immunoglobulin in Clindamycin-treated Patients With Streptococcal Toxic Shock Syndrome: A Systematic Review and Meta-analysis

Tom Parks  1 , Clare Wilson  2 , Nigel Curtis  3 , Anna Norrby-Teglund  4 , Shiranee Sriskandan  2
Affiliations
Meta-Analysis

Polyspecific Intravenous Immunoglobulin in Clindamycin-treated Patients With Streptococcal Toxic Shock Syndrome: A Systematic Review and Meta-analysis

Tom Parks et al. Clin Infect Dis. .

Abstract

We evaluated the effect of intravenous immunoglobulin (IVIG) on mortality in clindamycin-treated streptococcal toxic shock syndrome using a meta-analysis. In association with IVIG, mortality fell from 33.7% to 15.7% with remarkable consistency across the single randomized and four nonrandomized studies.

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Figures

Figure 1.
Figure 1.
Forest plot showing the estimated risk ratio for mortality with or without intravenous immunoglobulin in clindamycin-treated streptococcal toxic shock syndrome.
See this image and copyright information in PMC

References

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