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Comment
. 2018 Jul;26(7):559-560.
doi: 10.1016/j.tim.2018.05.003. Epub 2018 May 19.

Engineering E. coli to Have a Hybrid Archaeal/Bacterial Membrane

Laura Villanueva  1
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Engineering E. coli to Have a Hybrid Archaeal/Bacterial Membrane

Laura Villanueva. Trends Microbiol. 2018 Jul.

Abstract

Bacteria and Archaea have membrane lipids with an opposite stereochemistry. The most plausible explanation for this differentiation implies an unstable heterochiral membrane stage. A recent study engineered Escherichia coli with a significant abundance of archaeal lipids showing higher robustness, disproving heterochirality as the driving force for this differentiation.

Keywords: Archaea; glycerol-1-phosphate; heterochiral; lipid divide; lipid membrane.

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