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Comment
. 2018 May 24;22(1):135.
doi: 10.1186/s13054-018-2007-z.

Prolonged corticosteroid treatment in acute respiratory distress syndrome: impact on mortality and ventilator-free days

Gianfranco Umberto Meduri  1 , Bram Rochwerg  2 , Djillali Annane  3 , Stephen M Pastores  4 ; Corticosteroid Guideline Task Force of SCCM and ESICM
Affiliations
Comment

Prolonged corticosteroid treatment in acute respiratory distress syndrome: impact on mortality and ventilator-free days

Gianfranco Umberto Meduri et al. Crit Care. .
No abstract available

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Competing interests

The authors declare that they have no competing interests.

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Figures

Fig. 1
Fig. 1
Hospital mortality in ARDS subgroup before day 14. Comparison between randomized trials at high risk of bias versus those at low risk of bias which investigated prolonged glucocorticoid (methylprednisolone or hydrocortisone) treatment in ARDS
See this image and copyright information in PMC

Comment on

References

    1. Blot M, Salmon-Rousseau A, Chavanet P, Piroth L. Do we know enough to recommend corticosteroids in acute respiratory distress syndrome? Crit Care. 2017;21(1):327. doi: 10.1186/s13054-017-1920-x. - DOI - PMC - PubMed
    1. Annane D, Pastores SM, Rochwerg B, et al. Guidelines to the diagnosis and management of critical illness-related corticosteroid insufficiency (CIRCI) in critically ill patients (part 1): Society of Critical Care Medicine (SCCM) and European Society of Intensive Care Medicine (ESICM) 2017. Crit Care Med. 2017;45:2078–2088. doi: 10.1097/CCM.0000000000002737. - DOI - PubMed
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    1. Meduri GU, Headley AS, Golden E, Carson SJ, Umberger RA, Kelso T, Tolley EA. Effect of prolonged methylprednisolone therapy in unresolving acute respiratory distress syndrome: a randomized controlled trial. JAMA. 1998;280(2):159–165. doi: 10.1001/jama.280.2.159. - DOI - PubMed
    1. Meduri GU, Golden E, Freire AX, Taylor E, Zaman M, Carson SJ, Gibson M, Umberger R. Methylprednisolone infusion in early severe ARDS: results of a randomized controlled trial. Chest. 2007;131(4):954–963. doi: 10.1378/chest.06-2100. - DOI - PubMed

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