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Review
. 2018;82(2):95-99.
doi: 10.17116/oftalma201882295-99.

[Capabilities of 18F-FET PET/CT in a patient with brain glioma (a case report and literature review)]

[Article in Russian]
Affiliations
Free article
Review

[Capabilities of 18F-FET PET/CT in a patient with brain glioma (a case report and literature review)]

[Article in Russian]
A I Pronin et al. Zh Vopr Neirokhir Im N N Burdenko. 2018.
Free article

Abstract

Positron emission tomography combined with computed tomography (PET/CT) enables assessment of not only anatomical and structural but also metabolic changes in tumor mass. 18F-fluoroethyl tyrosine (18F-FET) PET/CT is based on evaluation of transport of 18F-labeled tyrosine in tissues. We present a clinical case of a patient with a newly diagnosed brain tumor, demonstrating the capabilities of 18F-FET PET/CT in assessing the reliable volume and degree of tumor anaplasia, which is important when choosing the treatment approach for a patient.

Метод позитронно-эмиссионной томографии, совмещенной с компьютерной томографией (ПЭТ/КТ), дает возможность оценить не только анатомические и структурные, но и метаболические изменения в опухолевом образовании. ПЭТ/КТ с 18F-фторэтилтирозином (18F-ФЭТ) базируется на оценке характера транспорта аминокислоты тирозина, меченной 18F, в тканях. Представлено клиническое наблюдение пациента с впервые выявленным новообразованием головного мозга, демонстрирующее возможности ПЭТ/КТ с 18F-ФЭТ в оценке достоверного объема и степени анаплазии опухоли, что важно для определения тактики лечения пациента.

Keywords: 18F-FET; PET/CT; anaplastic astrocytoma; glioma.

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