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Comment
. 2019 Jan;21(1):256-257.
doi: 10.1038/s41436-018-0029-1. Epub 2018 May 24.

Response to Roberts et al. 2018: is breast cancer truly caused by MSH6 and PMS2 variants or is it simply due to a high prevalence of these variants in the population?

S W Ten Broeke  1 , M Suerink  2 , M Nielsen  2
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Free article
Comment

Response to Roberts et al. 2018: is breast cancer truly caused by MSH6 and PMS2 variants or is it simply due to a high prevalence of these variants in the population?

S W Ten Broeke et al. Genet Med. 2019 Jan.
Free article
No abstract available

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Comment in

  • Response to ten Broeke et al.
    Roberts ME, Zeinomar N, Solomon BD, Terry MB, Chung WK. Roberts ME, et al. Genet Med. 2019 Jan;21(1):258-259. doi: 10.1038/s41436-018-0031-7. Epub 2018 May 24. Genet Med. 2019. PMID: 29795440 Free PMC article. No abstract available.

Comment on

References

    1. Roberts ME, Jackson SA, Susswein LR, et al. MSH6 and PMS2 germ-line pathogenic variants implicated in Lynch syndrome are associated with breast cancer. Genet Med. 2018. https://doi.org/10.1038/gim.2017.254 . [Epub ahead of print]. - DOI
    1. ten Broeke SW, Brohet RM, Tops CM, et al. Lynch syndrome caused by germline PMS2 mutations: delineating the cancer risk. J Clin Oncol. 2015;33:319–25. - DOI
    1. Win AK, Jenkins MA, Dowty JG, et al. Prevalence and penetrance of major genes and polygenes for colorectal cancer. Cancer Epidemiol Biomarkers Prev. 2016;26:404–12. - DOI

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