Traditional Chinese medicine: herb-drug interactions with aspirin
- PMID: 29796686
- PMCID: PMC5966631
- DOI: 10.11622/smedj.2018051
Traditional Chinese medicine: herb-drug interactions with aspirin
Abstract
Traditional Chinese medicine (TCM)-based herbal therapies have gained increasing popularity worldwide, raising concerns of its efficacy, safety profile and potential interactions with Western medications. Antithrombotic agents are among the most common prescription drugs involved in herb-drug interactions, and this article focused on aspirin, one of the most widely used antiplatelet agents worldwide. We discussed herbs that have potential interactions by exploring Western and TCM approaches to thrombotic events. Common TCM indications for these herbs were also highlighted, including possible scenarios of their concurrent usage with aspirin. With greater awareness and understanding of potential herb-drug interactions, TCM and Western physicians may collaborate more closely to identify, treat and, most importantly, prevent adverse drug events.
Keywords: antiplatelet; aspirin; herb-drug interactions; traditional Chinese medicine.
Copyright: © Singapore Medical Association.
Figures
Similar articles
-
Interactions between traditional Chinese medicine and western drugs in Taiwan: A population-based study.Comput Methods Programs Biomed. 2015 Dec;122(3):462-70. doi: 10.1016/j.cmpb.2015.09.006. Epub 2015 Sep 10. Comput Methods Programs Biomed. 2015. PMID: 26470816
-
Interaction between warfarin and Chinese herbal medicines.Singapore Med J. 2015 Jan;56(1):11-8. doi: 10.11622/smedj.2015004. Singapore Med J. 2015. PMID: 25640094 Free PMC article. Review.
-
Interaction between Traditional Chinese Medicine and Anticoagulant/Antiplatelet Drugs.Curr Drug Metab. 2019;20(9):701-713. doi: 10.2174/1389200220666190827160212. Curr Drug Metab. 2019. PMID: 31453781 Review.
-
Interactions between clopidogrel and traditional Chinese medicine.J Thromb Thrombolysis. 2019 Oct;48(3):491-499. doi: 10.1007/s11239-019-01945-3. J Thromb Thrombolysis. 2019. PMID: 31471773 Review.
-
Interactions of antithrombotic herbal medicines with Western cardiovascular drugs.Pharmacol Res. 2020 Sep;159:104963. doi: 10.1016/j.phrs.2020.104963. Epub 2020 Jun 1. Pharmacol Res. 2020. PMID: 32497719 Review.
Cited by
-
Cytokine Storm in COVID-19: Insight into Pathological Mechanisms and Therapeutic Benefits of Chinese Herbal Medicines.Medicines (Basel). 2024 Jul 18;11(7):14. doi: 10.3390/medicines11070014. Medicines (Basel). 2024. PMID: 39051370 Free PMC article. Review.
-
Pharmacokinetics effects of chuanxiong rhizoma on warfarin in pseudo germ-free rats.Front Pharmacol. 2023 Jan 5;13:1022567. doi: 10.3389/fphar.2022.1022567. eCollection 2022. Front Pharmacol. 2023. PMID: 36686675 Free PMC article.
-
Influence of Gegenqinlian Decoction on Pharmacokinetics and Pharmacodynamics of Atorvastatin Calcium in Hyperlipidemic Rats.Eur J Drug Metab Pharmacokinet. 2022 Jan;47(1):117-126. doi: 10.1007/s13318-021-00738-5. Epub 2021 Dec 2. Eur J Drug Metab Pharmacokinet. 2022. PMID: 34855161
-
Combination of Traditional Chinese Medicine and Low-Molecular-Weight Heparin Prevents Deep Vein Thrombosis After Surgery: A Meta-Analysis.Clin Appl Thromb Hemost. 2019 Jan-Dec;25:1076029619890411. doi: 10.1177/1076029619890411. Clin Appl Thromb Hemost. 2019. PMID: 31867999 Free PMC article.
-
Use of herbal medicine by caregivers in the management of children with sickle cell disease in Mulago National Referral Hospital - Uganda.Pan Afr Med J. 2021 Jul 1;39:163. doi: 10.11604/pamj.2021.39.163.20740. eCollection 2021. Pan Afr Med J. 2021. PMID: 34548892 Free PMC article.
References
-
- Hsiao WL, Liu L. The role of traditional Chinese herbal medicines in cancer therapy--from TCM theory to mechanistic insights. Planta Med. 2010;76:1118–31. - PubMed
-
- Zhou SF, Zhou ZW, Li CG, et al. Identification of drugs that interact with herbs in drug development. Drug Discov Today. 2007;12:664–73. - PubMed
-
- Tan MG, Win MT, Khan SA. The use of complementary and alternative medicine in chronic pain patients in Singapore: a single-centre study. Ann Acad Med Singapore. 2013;42:133–7. - PubMed
-
- Dergal JM, Gold JL, Laxer DA, et al. Potential interactions between herbal medicines and conventional drug therapies used by older adults attending a memory clinic. Drugs Aging. 2002;19:879–86. - PubMed
-
- Saw JT, Bahari MB, Ang HH, Lim YH. Potential drug-herb interaction with antiplatelet/anticoagulant drugs. Complement Ther Clin Pract. 2006;12:236–41. - PubMed
Publication types
MeSH terms
Substances
LinkOut - more resources
Full Text Sources
Other Literature Sources