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. 2017 May 15;31(5):513-518.
doi: 10.7507/1002-1892.201612146.

[Early effectiveness of cervical disc replacement by using Pretic-I]

[Article in Chinese]
Hao Liu  1 , Yuxiao Deng  2 , Ziyang Liu  2 , Beiyu Wang  2 , Chen Ding  2 , Ying Hong  3 , Hua Chen  2 , Litai Ma  2
Affiliations

[Early effectiveness of cervical disc replacement by using Pretic-I]

[Article in Chinese]
Hao Liu et al. Zhongguo Xiu Fu Chong Jian Wai Ke Za Zhi. .

Abstract
in English, Chinese

Objective: To observe the early effectiveness of cervical disc replacement with Pretic-I, a new type artificial disc.

Methods: A retrospective analysis was made on the clinical data of 10 patients who underwent single segmental cervical disc replacement with Pretic-I from June to December 2014. Among 10 patients, 4 were male and 6 were female, with an average age of 40 years (range, 27-51 years). The mean disease duration was 15.4 months (range, 4-36 months). Affected segments located at C 4, 5 level in 1 case, at C 5, 6 level in 8 cases, and at C 6, 7 level in 1 case. The visual analogue scale (VAS), Japanese Orthopaedic Association (JOA) score, and neck disability index (NDI) were used to evaluate the clinical outcomes. Besides, the disc height and the range of motion (ROM) at operated level, and ROM of upper and lower adjacent level were measured to assess the function.

Results: The operation was successfully completed in all patients who were followed up for 12 months. No complications of aggravated nerve symptoms, vertebral artery injury, esophagotracheal fistula, cerebrospinal fluid leakage, incision infection, hematoma and prosthetic loosening were observed during follow-up. The VAS score, JOA score, and NDI significantly improved at each time point after operation when compared with preoperative scores ( P<0.05). The height of intervertebral disc at operated level was significantly increased at immediate and 3 months after operation when compared with preoperative one ( P<0.05), but no significant difference was found between at 6 months or 12 months after operation and at pre-operation ( P>0.05). No significant difference was shown in the ROM at operated level, and ROM of upper and lower adjacent level between at pre-operation and at each time point after operation ( P>0.05).

Conclusion: The early effctiveness of cervical disc replacement using Pretic-I is satisfactory. The symptoms can be relieved significantly and the dynamic features of the operated level, as well as the upper and lower adjacent levels, are well preserved.

目的: 总结采用一种新型人工颈椎间盘（Pretic-Ⅰ）行人工颈椎间盘置换术的早期疗效。.

方法: 回顾分析 2014 年 6 月—12 月采用 Pretic-Ⅰ 人工椎间盘置换术治疗的 10 例单间隙颈椎间盘突出症患者临床资料。其中男 4 例，女 6 例；年龄 27～51 岁，平均 40 岁。病程 4～36 个月，平均 15.4 个月。手术节段：C 4、5 1 例，C 5、6 8 例，C 6、7 1 例。术前、术后即刻及术后 3、6、12 个月采用疼痛视觉模拟评分（VAS）、日本骨科协会（JOA）评分、颈椎功能障碍指数（NDI）评价疗效；于颈椎X线片测量目标椎间隙高度，目标椎间隙及上、下位相邻椎间隙活动度，评价颈椎运动功能。.

结果: 患者均顺利完成手术并获随访 12 个月。随访期间未出现神经症状加重、椎动脉损伤、食管气管瘘、脑脊液漏、切口感染、血肿形成、假体松动、脱落等并发症。术后各时间点 VAS 评分、JOA 评分及 NDI 均较术前显著改善（ P<0.05）。术后即刻及 3 个月时目标椎间隙高度显著高于术前（ P<0.05）；术后 6、12 个月与术前比较差异无统计学意义（ P>0.05）。术后各时间点目标椎间隙及上、下位相邻椎间隙活动度与术前比较差异均无统计学意义（ P>0.05）。.

结论: Pretic-Ⅰ 人工颈椎间盘置换术治疗单间隙颈椎间盘突出症早期疗效良好，临床症状改善明显，同时较好地维持了手术节段及上、下相邻间隙的运动特征。.

Keywords: Pretic-I artificial disc; cervical disc herniation; cervical disc replacement.

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Figures

图 1
图 1
Pretic-I artificial disc for cervical spine　a. Lateral view of the disc (held by controller); b. Superior view of the cranial plate; c. Inferior view of the cranial plate; d. Superior view of the caudal plate; e. Inferior view of the caudal plate Pretic-Ⅰ 人工椎间盘大体观察　a. 椎间盘侧面观（把持器把持下）；b. 头端终板上面观；c. 头端终板下面观；d. 尾端终板上面观；e. 尾端终板下面观
图 2
图 2
A 42-year-old male patient underwent disc replacement at C5, 6 　From left to right for X-ray films of cervical spine at anteroposterior, lateral (neutral), flexion, and extension position a. Before operation; b. At immediate after operation; c. At 3 months after operation; d. At 6 months after operation; e. At 12 months after operation 患者，男，42岁，C5、6 椎间盘置换 X 线片　从左至右分别为颈椎正位、侧位（中立位）、过屈位、过伸位 a. 术前；b. 术后即刻；c. 术后 3 个月；d. 术后 6 个月；e. 术后 12 个月
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