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. 2018 Aug;24(8):1598-1599.
doi: 10.3201/eid2408.180588. Epub 2018 Aug 17.

Phylogeny of Yellow Fever Virus, Uganda, 2016

Holly R Hughes, John Kayiwa, Eric C Mossel, Julius Lutwama, J Erin Staples, Amy J Lambert

Phylogeny of Yellow Fever Virus, Uganda, 2016

Holly R Hughes et al. Emerg Infect Dis. 2018 Aug.

Abstract

In April 2016, a yellow fever outbreak was detected in Uganda. Removal of contaminating ribosomal RNA in a clinical sample improved the sensitivity of next-generation sequencing. Molecular analyses determined the Uganda yellow fever outbreak was distinct from the concurrent yellow fever outbreak in Angola, improving our understanding of yellow fever epidemiology.

Keywords: 2016. Emerg Infect Dis. 2018 Aug [date cited]. https://doi.org/10.3201/eid2408.180588; Kayiwa J; Lambert AJ. Phylogeny of yellow fever virus; Lutwama J; Mossel EC; Staples JE; Suggested citation for this article: Hughes HR; Uganda.

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Figures

Figure
Figure
Bayesian maximum clade credibility tree of the Uganda 2016 YFV. Phylogenetic inference of the Uganda 2016 YFV strain (asterisk) representing partial coding regions of the membrane and envelope genes compared with reference YFV genotypes. Posterior probabilities are shown for each branch. Reference YFV strains are labeled with strain designation and GenBank accession numbers. YFV, yellow fever virus. Scale bar indicates nucleotide substitutions per site.
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