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. 2018 Jun 5;319(21):2231-2233.
doi: 10.1001/jama.2018.5616.

Use of Conservative Management for Low-Risk Prostate Cancer in the Veterans Affairs Integrated Health Care System From 2005-2015

Affiliations

Use of Conservative Management for Low-Risk Prostate Cancer in the Veterans Affairs Integrated Health Care System From 2005-2015

Stacy Loeb et al. JAMA. .

Abstract

This study uses US Department of Veterans Affairs (VA) data to characterize trends in the use of watchful waiting and active surveillance as strategies for managing low-risk prostate cancer in US veterans from 2005 through 2015.

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Conflict of interest statement

Conflict of Interest Disclosures: All authors have completed and submitted the ICMJE Form for Disclosure of Potential Conflicts of Interest. Dr Loeb reported consulting for Lilly, MDx Health, GenomeDx, and General Electric and receiving personal fees from Astellas, Sanofi, Minomic, and Boehringer Ingelheim. Dr Makarov reported consulting for the US Food and Drug Administration. Dr Lepor reported previously holding shares in SonaCare Medical and receiving research support from and serving on the advisory board for Genomic Health. No other disclosures were reported.

Figures

Figure.
Figure.. Proportion of US Veterans With Low-Risk Prostate Cancer Receiving Conservative Management (Active Surveillance or Watchful Waiting) From 2005-2015, by Agea
aIn the total cohort (N = 125 083), 68 463 were <65 y, of whom 43% received conservative management; 56 620 of men were ≥65 y, of whom 54% received conservative management.

References

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    1. Cooperberg MR, Carroll PR. Trends in management for patients with localized prostate cancer, 1990-2013. JAMA. 2015;314(1):80-82. - PubMed
    1. Moschini M, Fossati N, Sood A, et al. . Contemporary management of prostate cancer patients suitable for active surveillance. Eur Urol Focus. doi:10.1016/j.euf.2016.06.001 - DOI - PubMed
    1. Loeb S, Folkvaljon Y, Curnyn C, Robinson D, Bratt O, Stattin P. Uptake of active surveillance for very-low-risk prostate cancer in Sweden. JAMA Oncol. 2017;3(10):1393-1398. - PMC - PubMed
    1. Loeb S, Curnyn C, Fagerlin A, et al. . Qualitative study on decision-making by prostate cancer physicians during active surveillance. BJU Int. 2017;120(1):32-39. - PMC - PubMed

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