Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2018 Nov 28;67(12):1915-1918.
doi: 10.1093/cid/ciy439.

Respiratory Syncytial Virus Hospitalization During Pregnancy in 4 High-income Countries, 2010-2016

Annette K Regan  1   2 , Nicola P Klein  3 , Gayle Langley  4 , Steven J Drews  5   6 , Sarah Buchan  7   8   9 , Sarah Ball  10 , Jeffrey C Kwong  7   8   9   11   12 , Allison Naleway  13 , Mark Thompson  4 , Brandy E Wyant  10 , Avram Levy  14   15 , Hannah Chung  7 , Becca Feldman  16 , Mark A Katz  16   17   18 ; PREVENT Group
Collaborators, Affiliations

Respiratory Syncytial Virus Hospitalization During Pregnancy in 4 High-income Countries, 2010-2016

Annette K Regan et al. Clin Infect Dis. .

Abstract

Few studies have addressed respiratory syncytial virus (RSV) infection during pregnancy. Among 846 pregnant women hospitalized with respiratory illness and tested for RSV, 21 (2%) were RSV positive, of whom 8 (38%) were diagnosed with pneumonia. Despite study limitations, these data can help inform decisions about RSV prevention strategies.

PubMed Disclaimer

Conflict of interest statement

N. P. K. reports grants from GlaxoSmithKline, Sanofi Pasteur, Pfizer, Protein Science, Merck & Co, MedImmune, Novartis (now GSK), and Dynavax outside the submitted work. S. J. D. reports being a content advisor to Johnson & Johnson (Jannsen Pharmaceuticals) on respiratory virus testing. A. N. reports grants from Pfizer, MedImmune/Astra Zeneca, and Merck outside the submitted work.

Members of the PREVENT workgroup in addition to the named authors include the following: Centers for Disease Control and Prevention (Eduardo Azziz-Baumgartner), Abt Associates (Pat Shifflet, Rebecca V. Fink), Institute for Clinical Evaluative Sciences (ICES) (Deshayne Fell), Clalit Research Institute (Dan Riesel), Central Virology Laboratory, Israel Ministry of Health (Michal Mandelboim), Israel Center for Disease Control, Israel Ministry of Health (Aharona Glatman-Freedman), Department of Health Western Australia (Paul Effler), and Kaiser Permanente Northern California (Ned Lewis).

In Western Australia, the authors thank the Linkage and Client Services Teams at the Data Linkage Branch (Department of Health Western Australia) as well as the Data Custodians for the Midwives Notification System, the Hospital Morbidity Data Collection, the WA Antenatal Vaccination Database, PathWest Laboratory Medicine Data Collection, and the Western Australia Notifiable Infectious Disease Database.

In Ontario, the authors thank the laboratory data providers from PHO (Jonathan Gubbay), Children’s Hospital of Eastern Ontario (Timothy Karnauchow and Dayre McNally), North York General Hospital (Kevin Katz), St. Joseph’s Healthcare Hamilton (Marek Smieja), Sinai Health System and University Health Network (Allison McGeer), Sunnybrook Health Sciences Centre (Andrew Simor), and William Osler Health System (David Richardson).

In Israel, the authors thank Noam Barda, Maya Leventar-Roberts, and Ilan Gofer.

In Alberta, the authors thank Kimberley Simmonds, Stephanie M Booth, Margaret Russell, and Lawrence W. Svenson.

At Kaiser Permanente Northwest, the authors thank Bradley Crane and Matthew Slaughter. At Kaiser Permanente Northern California, the authors thank Kristin Goddard, Edwin Lewis, and Sharareh Modaressi. At Kaiser Permanente Washington, the authors thank Lisa Ross and Lawrence Madziwa.

References

    1. Shi T, McAllister DA, O’Brien KL, et al. Global, regional, and national disease burden estimates of acute lower respiratory infections due to respiratory syncytial virus in young children in 2015: a systematic review and modelling study. Lancet 2017; 390:946–58. - PMC - PubMed
    1. Munoz FM. Respiratory syncytial virus in infants: is maternal vaccination a realistic strategy? Curr Opin Infect Dis 2015; 28:221–4. - PubMed
    1. Matias G, Taylor R, Haguinet F, Schuck-Paim C, Lustig R, Shinde V. Estimates of hospitalization attributable to influenza and RSV in the US during 1997–2009, by age and risk status. BMC Public Health 2017; 17:271. - PMC - PubMed
    1. Colosia AD, Yang J, Hillson E, et al. The epidemiology of medically attended respiratory syncytial virus in older adults in the United States: a systematic review. PLoS One 2017; 12:e0182321. - PMC - PubMed
    1. Kim L, Rha B, Abramson JS, et al. Identifying gaps in respiratory syncytial virus disease epidemiology in the United States prior to the introduction of vaccines. Clin Infect Dis 2017; 65:1020–5. - PMC - PubMed

Publication types