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Case Reports
. 2018 Aug 1;4(8):1118-1119.
doi: 10.1001/jamaoncol.2018.0186.

Hypopigmented Skin Lesions After Immunotherapy

Ecaterina Ileana Dumbrava  1 , Doina Ivan  2 , Vivek Subbiah  1
Affiliations
Case Reports

Hypopigmented Skin Lesions After Immunotherapy

Ecaterina Ileana Dumbrava et al. JAMA Oncol. .
No abstract available

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Figures

Figure 1:
Figure 1:
Clinical photograph of the left lower extremity with hypopigmented lesions (1A) compared with prior skin examination (1B).
Figure 1:
Figure 1:
Clinical photograph of the left lower extremity with hypopigmented lesions (1A) compared with prior skin examination (1B).
Figure 2:
Figure 2:
The skin biopsy (high power, magnification X20) reveals significant pigment incontinence in addition to interface and lichenoid dermatitis and a reduced number of junctional melanocytes
See this image and copyright information in PMC

References

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    1. Nakamura Y, Tanaka R, Asami Y, et al. Correlation between vitiligo occurrence and clinical benefit in advanced melanoma patients treated with nivolumab: A multi-institutional retrospective study. J Dermatol. 2017;44(2):117–122. - PubMed
    1. Hua C, Boussemart L, Mateus C, et al. Association of Vitiligo With Tumor Response in Patients With Metastatic Melanoma Treated With Pembrolizumab. JAMA Dermatology. 2016;152(1):45. - PubMed

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