Atrial natriuretic peptide in the heart and pancreas
Affiliations
- PMID: 2980110
Item in Clipboard
Atrial natriuretic peptide in the heart and pancreas
Histol Histopathol.
1986 Apr.
Abstract
We used antisera to pure atrial natriuretic peptide to localise this peptide by immunocytochemistry in rat and human tissue. We showed that both rat and human atrial cardiocytes gave a positive reaction while ventricular cardiocytes were consistently negative. Peripheral islet cells in rat but not in human pancreas also showed positive staining for ANP. We showed by double labelling techniques that the ANP was present in the glucagon containing cells.
Similar articles
-
Ventricular expression of atrial and brain natriuretic peptides in dilated cardiomyopathy. An immunohistocytochemical study of the endomyocardial biopsy specimens using specific monoclonal antibodies.Am J Pathol. 1993 Jan;142(1):107-16. Am J Pathol. 1993. PMID: 8424448 Free PMC article.
-
Immunoreactive atrial natriuretic peptide and dopamine beta-hydroxylase in myocytes and chromaffin cells of the heart of the African lungfish, Protopterus aethiopicus.Gen Comp Endocrinol. 1994 Jul;95(1):1-12. doi: 10.1006/gcen.1994.1096. Gen Comp Endocrinol. 1994. PMID: 7926645
-
Changes in expression of P2 receptors in rat and mouse pancreas during development and ageing.Cell Tissue Res. 2001 Dec;306(3):373-83. doi: 10.1007/s004410100458. Epub 2001 Oct 10. Cell Tissue Res. 2001. PMID: 11735037
-
Equine cardiodilatin/ atrial natriuretic peptide. Primary structure and immunohistochemical localization in auricular cardiocytes.Acta Anat (Basel). 1998;162(4):185-93. Acta Anat (Basel). 1998. PMID: 9831767
-
Immunocytochemical localization of atrial natriuretic factor in the heart and salivary glands.Histochemistry. 1984;80(2):113-27. doi: 10.1007/BF00679984. Histochemistry. 1984. PMID: 6370928
Cited by
-
C-type natriuretic peptide receptor expression in pancreatic alpha cells.Histochem Cell Biol. 2009 Jul;132(1):95-103. doi: 10.1007/s00418-009-0591-3. Epub 2009 Apr 8. Histochem Cell Biol. 2009. PMID: 19352691
-
The exocrine pancreas is an extracardiac source of atrial natriuretic peptide.Pflugers Arch. 2019 Jun;471(6):915-924. doi: 10.1007/s00424-018-02247-y. Epub 2019 Jan 8. Pflugers Arch. 2019. PMID: 30623208
-
Atrial natriuretic peptide (ANP) acts via specific binding sites on cGMP system of rat pancreatic islets without affecting insulin release.Naunyn Schmiedebergs Arch Pharmacol. 1989 Mar;339(3):348-53. doi: 10.1007/BF00173590. Naunyn Schmiedebergs Arch Pharmacol. 1989. PMID: 2542810
-
Atrial natriuretic peptide in peripheral organs other than the heart.Klin Wochenschr. 1990 Jul 17;68(14):699-708. doi: 10.1007/BF01647577. Klin Wochenschr. 1990. PMID: 2144031 Review.
-
Immunohistochemical and ultrastructural localisation of peptide-containing nerves and myocardial cells in the human atrial appendage.Cell Tissue Res. 1988 Oct;254(1):155-66. doi: 10.1007/BF00220029. Cell Tissue Res. 1988. PMID: 2973836