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Observational Study
. 2018 Jul;38(7):908-916.
doi: 10.1038/s41372-017-0020-8. Epub 2018 May 29.

Accuracy of the Bayley-II mental development index at 2 years as a predictor of cognitive impairment at school age among children born extremely preterm

Thomas M O'Shea  1 , Robert M Joseph  2 , Elizabeth N Allred  3   4 , H Gerry Taylor  5 , Alan Leviton  3   4 , Tim Heeren  6 , Laurie M Douglass  7 , Jean A Frazier  8 , Hernan Jara  9 , Karl C K Kuban  7 ; ELGAN Study Investigators
Collaborators, Affiliations
Observational Study

Accuracy of the Bayley-II mental development index at 2 years as a predictor of cognitive impairment at school age among children born extremely preterm

Thomas M O'Shea et al. J Perinatol. 2018 Jul.

Abstract

Objective: To describe the accuracy of the Bayley Scales of Infant Development-Second Edition (BSID-II) Mental Development Index (MDI) at 2 years of age for prediction of cognitive function at school age of children born extremely preterm.

Design: Study participants were enrolled in the Extremely Low Gestational Age Newborn Study between 2002 and 2004. Two-thirds of surviving children (n = 795) were assessed at 2 years with the BSID-II and at 10 years with an intelligence quotient (IQ) test. We computed test characteristics for a low MDI (<70), including predictive value positive.

Results: Almost two-thirds of children with a low MDI had a normal IQ (≥ 70) at 10 years. Concordance between MDI and IQ was highest among children with major motor and/or sensory impairment, and when MDI was adjusted for gestational age.

Conclusion: Most children born extremely preterm with low BSID-II MDI at 2 years have normal intelligence at school age.

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Conflict of interest statement

None of the authors has relevant financial interests, activities, relationships, or affiliations.

Figures

Figure 1
Figure 1
Frequency distribution for DAS IQ at 10 years minus BSID MDI at 2 years. The overlying normal curve is calculated using the mean and standard deviation of the difference.
See this image and copyright information in PMC

References

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