Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 1985 Jan;53(1):335-9.
doi: 10.1128/JVI.53.1.335-339.1985.

A determinant of polyomavirus virulence enhances virus growth in cells of renal origin

J B Bolen, S E Fisher, K Chowdhury, T C Shan, J E Williams, C J Dawe, M A Israel

A determinant of polyomavirus virulence enhances virus growth in cells of renal origin

J B Bolen et al. J Virol. 1985 Jan.

Abstract

We have identified a strain of polyomavirus, Py(L), which is unusual in causing acute morbidity and early death after inoculation of newborn mice. We determined that these animals died of kidney failure associated with extensive, virus-mediated destruction of renal tissue. Interestingly, the Py(L) strain infects baby mouse kidney cell cultures more efficiently than do other strains.

PubMed Disclaimer

References

    1. J Natl Cancer Inst. 1966 Jun;36(6):1121-36 - PubMed
    1. Virology. 1974 Feb;57(2):475-90 - PubMed
    1. J Mol Biol. 1967 Jun 14;26(2):365-9 - PubMed
    1. J Natl Cancer Inst. 1959 Dec;23:1441-75 - PubMed
    1. Proc Natl Acad Sci U S A. 1983 Jan;80(1):70-4 - PubMed

LinkOut - more resources