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. 1985 Jan;40(1):9-17.
doi: 10.1016/0092-8674(85)90303-4.

Nucleotide sequence of the AIDS virus, LAV

S Wain-Hobson, P Sonigo, O Danos, S Cole, M Alizon

Nucleotide sequence of the AIDS virus, LAV

S Wain-Hobson et al. Cell. 1985 Jan.

Abstract

The complete 9193-nucleotide sequence of the probable causative agent of AIDS, lymphadenopathy-associated virus (LAV), has been determined. The deduced genetic structure is unique: it shows, in addition to the retroviral gag, pol, and env genes, two novel open reading frames we call Q and F. Remarkably, Q is located between pol and env and F is half-encoded by the U3 element of the LTR. These data place LAV apart from the previously characterized family of human T cell leukemia/lymphoma viruses.

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