doi: 10.1016/0166-0934(85)90085-0.
Radioimmunoassay for detection of VP1 specific neutralizing antibodies of foot and mouth disease virus
- PMID: 2982892
- DOI: 10.1016/0166-0934(85)90085-0
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Radioimmunoassay for detection of VP1 specific neutralizing antibodies of foot and mouth disease virus
J Virol Methods.
1985 Jan.
Abstract
A solid-phase radioimmunoassay was developed for the detection of antibodies against a specific region of the VP1 protein of the A24 and 01 serotypes of foot and mouth disease virus. The antibody titers from the radioimmunoassay showed a positive correlation with neutralizing antibody titers determined by a mouse protection assay. The specificity of the assay resides in the peptide used as antigen. The assay is rapid, reproducible and does not require the use of whole virions.
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