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. 1985 Mar;53(3):988-9.
doi: 10.1128/JVI.53.3.988-989.1985.

A fragment of the simian virus 40 early genome can induce tumors in nude mice

S Pan, L M Sompayrac, B B Knowles, K J Danna

A fragment of the simian virus 40 early genome can induce tumors in nude mice

S Pan et al. J Virol. 1985 Mar.

Abstract

Cell lines transformed by simian virus 40 mutant F8dl (deleted from 0.168 to 0.424 map units, corresponding to the carboxy-terminal 62% of the wild-type simian virus 40 large tumor antigen) are tumorigenic in nude mice. Four of five C3H10T1/2 cell lines transformed by F8dl were tumorigenic in nude mice, whereas two of two wild-type transformants were tumorigenic.

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