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. 1985 Apr;18(4):431-3.
doi: 10.1002/ajh.2830180414.

Alpha globin gene rearrangements in Polynesians are not associated with malaria

R J Trent, K N Mickleson, T Wilkinson, J Yakas, R Bluck, M Dixon, A W Liley, H Kronenberg

Alpha globin gene rearrangements in Polynesians are not associated with malaria

R J Trent et al. Am J Hematol. 1985 Apr.

Abstract

Using gene mapping, 16.3% of Polynesians were shown to have alpha thalassemia. These results are surprising since malaria is not found in Polynesia. Moreover, triplicated alpha gene rearrangements were identified in a further 7.7%, a frequency not seen in other populations.

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