Sterigmatocystin: A mycotoxin to be seriously considered
- PMID: 29842907
- DOI: 10.1016/j.fct.2018.05.057
Sterigmatocystin: A mycotoxin to be seriously considered
Abstract
Sterigmatocystin is a carcinogenic compound that affects several species of crops and several species of experimental animals. The sterigmatocystin biosynthetic pathway is the best known and most studied. The International Agency for Research on Cancer classifies sterigmatocystin in the Group 2B. Three groups of analytical methods to determine sterigmatocystin in food can be found: chromatographic, ELISA immunoassays and chemical sensors. In addition, sterigmatocystin is a precursor of aflatoxin B1 in those cases where cereals and/or food are contaminated with fungi capable of producing aflatoxins. Chemical structures of sterigmatocystin and aflatoxin B1 are similar. These mycotoxins are pathogens of animals and cereals, producing a major economic impact on biotechnology and agricultural and food industries. This review summarizes different aspects related to sterigmatocystin such as its biosynthesis, toxicological studies and analytical methods for its determination.
Keywords: Analytical methods; Foods; Mycotoxins; Sterigmatocystin.
Copyright © 2018. Published by Elsevier Ltd.
Similar articles
-
Mycotoxins: food contamination, mechanism, carcinogenic potential and preventive measures.Mutat Res. 1991 Mar-Apr;259(3-4):291-306. doi: 10.1016/0165-1218(91)90124-5. Mutat Res. 1991. PMID: 2017214 Review.
-
Survey of aflatoxins, ochratoxin A, zearalenone, and sterigmatocystin in some Brazilian foods by using multi-toxin thin-layer chromatographic method.J Assoc Off Anal Chem. 1989 Jan-Feb;72(1):22-6. J Assoc Off Anal Chem. 1989. PMID: 2523887
-
Bioautographic detection of mycotoxins on thin-layer chromatograms.J Chromatogr. 1976 Jan 7;116(1):155-61. doi: 10.1016/s0021-9673(00)83710-3. J Chromatogr. 1976. PMID: 1245565
-
Occurrence and risk assessment of sterigmatocystin in agricultural products and processed foods in Korea.Food Addit Contam Part A Chem Anal Control Expo Risk Assess. 2022 Feb;39(2):373-381. doi: 10.1080/19440049.2021.1994156. Epub 2022 Jan 12. Food Addit Contam Part A Chem Anal Control Expo Risk Assess. 2022. PMID: 35020575
-
Sterigmatocystin: Occurrence, toxicity and molecular mechanisms of action - A review.Food Chem Toxicol. 2020 Dec;146:111802. doi: 10.1016/j.fct.2020.111802. Epub 2020 Oct 6. Food Chem Toxicol. 2020. PMID: 33035632 Review.
Cited by
-
Robust Profiling of Cytochrome P450s (P450ome) in Notable Aspergillus spp.Life (Basel). 2022 Mar 18;12(3):451. doi: 10.3390/life12030451. Life (Basel). 2022. PMID: 35330202 Free PMC article.
-
Probing the Interactions of 31 Mycotoxins with Xanthine Oxidase: Alternariol, Alternariol-3-Sulfate, and α-Zearalenol Are Allosteric Inhibitors of the Enzyme.Toxins (Basel). 2023 Mar 29;15(4):250. doi: 10.3390/toxins15040250. Toxins (Basel). 2023. PMID: 37104188 Free PMC article.
-
Emerging Mycotoxins in Cheese: Simultaneous Analysis of Aflatoxin M1, Aflatoxicol, and Sterigmatocystin by LC-MS/MS.Molecules. 2025 Apr 15;30(8):1774. doi: 10.3390/molecules30081774. Molecules. 2025. PMID: 40333770 Free PMC article.
-
Co-Occurrence of Mycotoxins in Feed for Cattle, Pigs, Poultry, and Sheep in Navarra, a Region of Northern Spain.Toxins (Basel). 2023 Feb 22;15(3):172. doi: 10.3390/toxins15030172. Toxins (Basel). 2023. PMID: 36977063 Free PMC article.
-
Ochratoxin A and Sterigmatocystin in Long-Ripened Grana Cheese: Occurrence, Wheel Rind Contamination and Effectiveness of Cleaning Techniques on Grated Products.Toxins (Basel). 2022 Apr 27;14(5):306. doi: 10.3390/toxins14050306. Toxins (Basel). 2022. PMID: 35622553 Free PMC article.
Publication types
MeSH terms
Substances
LinkOut - more resources
Full Text Sources
Other Literature Sources
Medical