Phage Therapy: What Have We Learned?
- PMID: 29843391
- PMCID: PMC6024844
- DOI: 10.3390/v10060288
Phage Therapy: What Have We Learned?
Abstract
In this article we explain how current events in the field of phage therapy may positively influence its future development. We discuss the shift in position of the authorities, academia, media, non-governmental organizations, regulatory agencies, patients, and doctors which could enable further advances in the research and application of the therapy. In addition, we discuss methods to obtain optimal phage preparations and suggest the potential of novel applications of phage therapy extending beyond its anti-bacterial action.
Keywords: anti-phage antibodies; experimental therapy; immunomodulation; phage cocktails; phage therapy; prophage.
Conflict of interest statement
A.G., R.M., M.Ł., A.G.-R , J.B., B.W.-D. and K.D. are co-inventors of patents owned by the Institute and covering phage preparations. Other authors declare that they have no conflict of interest.
References
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- Borysowski J., Międzybrodzki R., Górski A. Phage Therapy: Current Research and Application. Caister Academic Press; Norfolk, UK: 2014.
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- Azeredo J., Sillankorva J., editors. Bacteriophage Therapy: From Lab to Clinical Practice. Springer Nature, Humana Press; New York, NY, USA: 2018.
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- P.H.A.G.E. Phages for Human Applications Europe Group. [(accessed on 5 April 2018)]; Available online: www.p-h-a-g-e.org.
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