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Editorial
. 2018 Apr;10(Suppl 9):S1070-S1073.
doi: 10.21037/jtd.2018.04.35.

Steroids for sepsis: yes, no or maybe

Paul E Marik  1
Affiliations
Editorial

Steroids for sepsis: yes, no or maybe

Paul E Marik. J Thorac Dis. 2018 Apr.
No abstract available

PubMed Disclaimer

Conflict of interest statement

Conflicts of Interest: The author has no conflicts of interest to declare.

Comment on

  • Adjunctive Glucocorticoid Therapy in Patients with Septic Shock.
    Venkatesh B, Finfer S, Cohen J, Rajbhandari D, Arabi Y, Bellomo R, Billot L, Correa M, Glass P, Harward M, Joyce C, Li Q, McArthur C, Perner A, Rhodes A, Thompson K, Webb S, Myburgh J; ADRENAL Trial Investigators and the Australian–New Zealand Intensive Care Society Clinical Trials Group. Venkatesh B, et al. N Engl J Med. 2018 Mar 1;378(9):797-808. doi: 10.1056/NEJMoa1705835. Epub 2018 Jan 19. N Engl J Med. 2018. PMID: 29347874 Clinical Trial.

References

    1. Keh D, Boehnke T, Weber-Cartens S, et al. Immunologic and hemodynamic effects of "low-dose" hydrocortisone in septic shock: a double-blind, randomized, placebo-controlled, crossover study. Am J Respir Crit Care Med 2003;167:512-20. 10.1164/rccm.200205-446OC - DOI - PubMed
    1. Marik PE, Pastores SM, Annane D, et al. Recommendations for the diagnosis and management of corticosteroid insufficiency in critically ill adult patients: consensus statements from an international task force by the American College of Critical Care Medicine. Crit Care Med 2008;36:1937-49. 10.1097/CCM.0b013e31817603ba - DOI - PubMed
    1. Schumer W. Steroids in the treatment of clinical septic shock. Ann Surg 1976;184:333-41. 10.1097/00000658-197609000-00011 - DOI - PMC - PubMed
    1. Minneci PC, Deans KJ, Eichacker PQ, et al. The effects of steroids during sepsis depend on dose and severity of illness: an updated meta-analysis. Clin Microbiol Infect 2009;15:308-18. 10.1111/j.1469-0691.2009.02752.x - DOI - PMC - PubMed
    1. Annane D, Bellissant E, Bollaert PE, et al. Corticosteroids for treating sepsis. Cochrane Database Syst Rev 2015;12:CD002243. - PMC - PubMed

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