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. 2018 Dec 3;7(4):323-334.
doi: 10.1093/jpids/piy046.

Factors Associated With Pneumonia Severity in Children: A Systematic Review

Preston Dean  1 , Todd A Florin  2   3
Affiliations

Factors Associated With Pneumonia Severity in Children: A Systematic Review

Preston Dean et al. J Pediatric Infect Dis Soc. .

Abstract

Community-acquired pneumonia in children is associated with significant morbidity and mortality; however, data are limited in predicting which children will have negative outcomes, including clinical deterioration, severe disease, or development of complications. The Pediatric Infectious Diseases Society/Infectious Diseases Society of America (PIDS/IDSA) pediatric pneumonia guideline includes criteria that were modified from adult criteria and define pneumonia severity to assist with resource allocation and site-of-care decision-making. However, the PIDS/IDSA criteria have not been formally developed or validated in children. Definitions for mild, moderate, and severe pneumonia also vary across the literature, further complicating the development of standardized severity criteria. This systematic review summarizes (1) the current state of the evidence for defining and predicting pneumonia severity in children as well as (2) emerging evidence focused on risk stratification of children with pneumonia.

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Figure 1.
Results from literature search.
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References

    1. World Health Organization. Revised WHO Classification and Treatment of Childhood Pneumonia at Health Facilities: Evidence Summaries. Geneva: World Health Organization; 2014. - PubMed
    1. Jain S, Self WH, Wunderink RG, et al. Community-acquired pneumonia requiring hospitalization. N Engl J Med 2015; 373:2382. - PMC - PubMed
    1. Pfuntner A, Wier L, Stocks C.. Most Frequent Conditions in U.S. Hospitals, 2011. HCUP Statistical Brief #162. Rockville, MD: Agency for Healthcare Research and Quality, 2013. - PubMed
    1. Florin TA, French B, Zorc JJ, et al. Variation in emergency department diagnostic testing and disposition outcomes in pneumonia. Pediatrics 2013; 132:237–44. - PubMed
    1. Brogan TV, Hall M, Williams DJ, et al. Variability in processes of care and outcomes among children hospitalized with community-acquired pneumonia. Pediatr Infect Dis J 2012; 31:1036–41. - PMC - PubMed

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