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Review
. 2018 May 6:2018:9056173.
doi: 10.1155/2018/9056173. eCollection 2018.

Prospects of IL-2 in Cancer Immunotherapy

Hani Choudhry  1 , Nawal Helmi  1 , Wesam H Abdulaal  1 , Mustafa Zeyadi  1 , Mazin A Zamzami  1 , Wei Wu  2 , Maged Mostafa Mahmoud  3   4 , Mohiuddin Khan Warsi  5 , Mahmood Rasool  6 , Mohammad S Jamal  3
Affiliations
Review

Prospects of IL-2 in Cancer Immunotherapy

Hani Choudhry et al. Biomed Res Int. .

Abstract

IL-2 is a powerful immune growth factor and it plays important role in sustaining T cell response. The potential of IL-2 in expanding T cells without loss of functionality has led to its early use in cancer immunotherapy. IL-2 has been reported to induce complete and durable regressions in cancer patients but immune related adverse effects have been reported (irAE). The present review discusses the prospects of IL-2 in immunotherapy for cancer.

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Figures

Figure 1
Figure 1
Showing three different types of IL-2 receptors.
See this image and copyright information in PMC

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