Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 2018 May 28:6:13.
doi: 10.1186/s41038-018-0117-0. eCollection 2018.

Cell therapy for severe burn wound healing

Affiliations
Review

Cell therapy for severe burn wound healing

Zhe Li et al. Burns Trauma. .

Abstract

Cell therapy has emerged as an important component of life-saving procedures in treating burns. Over past decades, advances in stem cells and regenerative medicine have offered exciting opportunities of developing cell-based alternatives and demonstrated the potential and feasibility of various stem cells for burn wound healing. However, there are still scientific and technical issues that should be resolved to facilitate the full potential of the cellular devices. More evidence from large, randomly controlled trials is also needed to understand the clinical impact of cell therapy in burns. This article aims to provide an up-to-date review of the research development and clinical applications of cell therapies in burn wound healing and skin regeneration.

Keywords: Burn injuries; Cell therapy; Skin; Skin regeneration; Stem cells; Wound healing.

PubMed Disclaimer

Conflict of interest statement

Not applicableThe authors declare that they have no competing interests.

References

    1. Burns Fact. Aug 2017. http://www.who.int/mediacentre/factsheets/fs365/en/
    1. Hettiaratchy S, Dziewulski P. Pathophysiology and types of burns. BMJ. 2004;328:1427–1429. - PMC - PubMed
    1. Stanton RA, Billmire DA. Skin resurfacing for the burned patient. Clin Plast Surg. 2002;29(1):29–51. - PubMed
    1. Halim AS, Khoo TL, Yussof MSJ. Biologic and synthetic skin substitutes: an overview. Indian J Plast Surg. 2010;43(Suppl):S23–S28. - PMC - PubMed
    1. Billingham RE, Reynolds J. Transplantation studies on sheets of pure epidermal epithelium and on epidermal cell suspensions. Br J Plast Surg. 1952;5:25–36. - PubMed