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. 2018 May 31;173(6):1316-1317.
doi: 10.1016/j.cell.2018.05.030. Epub 2018 May 31.

Increasing T Cell Versatility with SUPRA CARs

Yvonne Y Chen  1
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Increasing T Cell Versatility with SUPRA CARs

Yvonne Y Chen. Cell. .
Free article

Abstract

Chimeric antigen receptor (CAR) T cells offer a promising treatment option for advanced cancers resistant to standard therapy. Here, Cho et al. report a split-CAR design that enables the engineering of multi-feature CAR-T cells, aiming to address current challenges limiting the safety and efficacy of CAR-T cells for cancer treatment.

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