Resident T cells stand up to HIV

Nadia R Roan^{1

2}

Affiliations

¹ Department of Urology, University of California, San Francisco, San Francisco, CA 94158, USA. nadia.roan@ucsf.edu.
² Gladstone Institute of Virology and Immunology, University of California, San Francisco, San Francisco, CA 94158, USA.

Comment

Nadia R Roan. Sci Immunol. 2018.

. 2018 Jun 1;3(24):eaat6121.

doi: 10.1126/sciimmunol.aat6121.

Nadia R Roan^{1

2}

¹ Department of Urology, University of California, San Francisco, San Francisco, CA 94158, USA. nadia.roan@ucsf.edu.
² Gladstone Institute of Virology and Immunology, University of California, San Francisco, San Francisco, CA 94158, USA.

Abstract

HIV-specific resident memory T cells are abundant in lymphoid tissues of elite controllers and exhibit distinct functional properties.

Identification and characterization of HIV-specific resident memory CD8⁺ T cells in human lymphoid tissue.
Buggert M, Nguyen S, Salgado-Montes de Oca G, Bengsch B, Darko S, Ransier A, Roberts ER, Del Alcazar D, Brody IB, Vella LA, Beura L, Wijeyesinghe S, Herati RS, Del Rio Estrada PM, Ablanedo-Terrazas Y, Kuri-Cervantes L, Sada Japp A, Manne S, Vartanian S, Huffman A, Sandberg JK, Gostick E, Nadolski G, Silvestri G, Canaday DH, Price DA, Petrovas C, Su LF, Vahedi G, Dori Y, Frank I, Itkin MG, Wherry EJ, Deeks SG, Naji A, Reyes-Terán G, Masopust D, Douek DC, Betts MR. Buggert M, et al. Sci Immunol. 2018 Jun 1;3(24):eaar4526. doi: 10.1126/sciimmunol.aar4526. Sci Immunol. 2018. PMID: 29858286 Free PMC article.