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. 2018 Jun 1;22(6):792-793.
doi: 10.1016/j.stem.2018.04.023.

Spotlight on Glycolysis: A New Target for Cord Blood Expansion

Andrea M Patterson  1 , Louis M Pelus  2
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Spotlight on Glycolysis: A New Target for Cord Blood Expansion

Andrea M Patterson et al. Cell Stem Cell. .
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Abstract

Umbilical cord blood (UCB) is a highly valuable but low-quantity source of hematopoietic stem cells (HSCs) for life-saving transplantations. Recently in Nature Medicine, Guo et al. (2018) found that antagonism of a glycolysis-blocking pathway enhances ex vivo expansion of long-term HSCs from human UCB.

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