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. 2018 Sep;131(9):1118-1124.
doi: 10.1016/j.amjmed.2018.04.040. Epub 2018 Jun 1.

Prevalence of Anxiety and Depression Symptoms in Patients with Myocardial Infarction with Non-Obstructive Coronary Arteries

Maria Daniel  1 , Stefan Agewall  2 , Felix Berglund  3 , Kenneth Caidahl  4 , Olov Collste  3 , Christina Ekenbäck  5 , Mats Frick  3 , Loghman Henareh  6 , Tomas Jernberg  5 , Karin Malmqvist  5 , Karin Schenck-Gustafsson  7 , Jonas Spaak  5 , Örjan Sundin  8 , Peder Sörensson  9 , Shams Y-Hassan  6 , Claes Hofman-Bang  5 , Per Tornvall  3
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Prevalence of Anxiety and Depression Symptoms in Patients with Myocardial Infarction with Non-Obstructive Coronary Arteries

Maria Daniel et al. Am J Med. 2018 Sep.

Abstract

Background: Myocardial infarction with non-obstructive coronary arteries is a working diagnosis for several heart disorders. Previous studies on anxiety and depression in patients with myocardial infarction with non-obstructive coronary arteries are lacking. Our aim was to investigate the prevalence of anxiety and depression among patients with myocardial infarction with non-obstructive coronary arteries.

Methods: We included 99 patients with myocardial infarction with non-obstructive coronary arteries together with age- and sex-matched control groups who completed the Beck Depression Inventory and the Hospital Anxiety and Depression Scale (HADS) 3 months after the acute event.

Results: Using the Beck Depression Inventory, we found that the prevalence of depression in patients with myocardial infarction with non-obstructive coronary arteries (35%) was higher than in healthy controls (9%; P = .006) and similar to that of patients with coronary heart disease (30%; P = .954). Using the HADS anxiety subscale, we found that the prevalence of anxiety in patients with myocardial infarction with non-obstructive coronary arteries (27%) was higher than in healthy controls (9%; P = .002) and similar to that of patients with coronary heart disease (21%; P = .409). Using the HADS depression subscale, we found that the prevalence of depression in patients with myocardial infarction with non-obstructive coronary arteries (17%) was higher than in healthy controls (4%; P = .003) and similar to that of patients with coronary heart disease (13%; P = .466). Patients with myocardial infarction with non-obstructive coronary arteries and takotsubo syndrome scored higher on the HADS anxiety subscale than those without (P = .028).

Conclusions: This is the first study on the mental health of patients with myocardial infarction with non-obstructive coronary arteries to show that prevalence rates of anxiety and depression are similar to those in patients with coronary heart disease.

Keywords: Beck Depression Inventory; Hospital Anxiety and Depression Scale; Myocardial infarction; Myocardial infarction with non-obstructive coronary arteries; Takotsubo syndrome.

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