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. 2018 Apr;6(8):148.
doi: 10.21037/atm.2018.03.16.

Alcohol use disorders before and after bariatric surgery: a systematic review and meta-analysis

Hamza Azam  1 , Sara Shahrestani  1 , Kevin Phan  1   2
Affiliations

Alcohol use disorders before and after bariatric surgery: a systematic review and meta-analysis

Hamza Azam et al. Ann Transl Med. 2018 Apr.

Abstract

Background: There have been increasing reports of increased risk of alcohol use disorder (AUD) in the post bariatric surgery patient. The aim of this systematic review and meta-analysis is to observe the rate of AUD in the postoperative period following bariatric surgery for weight management.

Methods: Electronic searches were performed using six databases from their dates of inception to January 2017. Studies observing the trend in AUD post bariatric surgery were identified. Data for relevant endpoint was extracted and analysed.

Results: Ten studies were identified for inclusion of analyses. One year post operatively pooled odds were 1.004 [95% confidence interval (CI), 0.921-1.094; P=0.935], with no significant difference found in the proportion of patients with AUD at 1 year vs. pre-surgery. Two years post operatively pooled odds were 0.981 (95% CI, 0.843-1.142; P=0.806), with no significant difference found in the proportion of patients with AUD at 2 years vs. pre-surgery. Three years post operatively pooled odds were 1.825 (95% CI, 1.53-2.178; P<0.001) with a significant increase in AUD particularly with gastric bypass surgery.

Conclusions: In conclusion, prevalence of AUD increases in patients undergoing gastric bypass surgery but not gastric banding. The risk of AUD was found to not be significantly increased in the first 2 years postoperatively but increasing after this period.

Keywords: Alcohol use disorder (AUD); Roux-en-Y gastric bypass (RYGB); bariatric surgery; gastric banding; gastric bypass; laparoscopic adjustable gastric banding (LAGB); obesity.

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Conflict of interest statement

Conflicts of Interest: The authors have no conflicts of interest to declare.

Figures

Figure 1
Figure 1
PRISMA chart for search strategy used in the present study.
Figure 2
Figure 2
Forest plot comparing the effect of bariatric surgery vs. control on AUD at 1 year.
Figure 3
Figure 3
Forest plot comparing the effect of bariatric surgery vs. control on AUD at 2 years.
Figure 4
Figure 4
Forest plot comparing the effect of bariatric surgery vs. control on AUD at ≥3 years.
See this image and copyright information in PMC

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