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Review
. 2018 Jun 2;6(2):47.
doi: 10.3390/diseases6020047.

Psoriasis and Microbiota: A Systematic Review

Farida Benhadou  1 , Dillon Mintoff  2 , Benjamin Schnebert  3 , Hok Bing Thio  4
Affiliations
Review

Psoriasis and Microbiota: A Systematic Review

Farida Benhadou et al. Diseases. .

Abstract

Background: Recent advances have highlighted the crucial role of microbiota in the pathophysiology of chronic inflammatory diseases as well as its impact on the efficacy of therapeutic agents. Psoriasis is a chronic, multifactorial inflammatory skin disorder, which has a microbiota distinct from healthy, unaffected skin.

Aim: Through an extensive review of the literature, we aim to discuss the skin and gut microbiota and redefine their role in the pathogenesis of psoriasis.

Conclusions: Unfortunately, the direct link between the skin microbiota and the pathogenesis of psoriasis remains to be clearly established. Apart from improving the course of psoriasis, selective modulation of the microbiota may increase the efficacy of medical treatments as well as attenuate their side effects.

Keywords: microbiota; prebiotics; probiotics; psoriasis.

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Conflict of interest statement

The authors declare no conflict of interest.

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