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Review
. 2018 Jun 4;16(6):194.
doi: 10.3390/md16060194.

Novel Natural Products from Extremophilic Fungi

Xuan Zhang  1 , Shou-Jie Li  2 , Jin-Jie Li  3 , Zi-Zhen Liang  4 , Chang-Qi Zhao  5
Affiliations
Review

Novel Natural Products from Extremophilic Fungi

Xuan Zhang et al. Mar Drugs. .

Abstract

Extremophilic fungi have been found to develop unique defences to survive extremes of pressure, temperature, salinity, desiccation, and pH, leading to the biosynthesis of novel natural products with diverse biological activities. The present review focuses on new extremophilic fungal natural products published from 2005 to 2017, highlighting the chemical structures and their biological potential.

Keywords: biological activity; extremophilic fungi; natural products.

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Conflict of interest statement

The authors declare that they have no conflict of interests.

Figures

Figure 1
Figure 1
Novel natural products derived from piezophilic fungi (compounds 1–9). * Absolute configuration is not determined.
Figure 1
Figure 1
Novel natural products derived from piezophilic fungi (compounds 1–9). * Absolute configuration is not determined.
Figure 2
Figure 2
Novel natural products derived from piezophilic fungi (compounds 10–14).
Figure 3
Figure 3
Novel natural products derived from piezophilic fungi (compounds 15–38). * Absolute configuration is not determined.
Figure 3
Figure 3
Novel natural products derived from piezophilic fungi (compounds 15–38). * Absolute configuration is not determined.
Figure 4
Figure 4
Novel natural products derived from piezophilic fungi (compounds 39–45).
Figure 4
Figure 4
Novel natural products derived from piezophilic fungi (compounds 39–45).
Figure 5
Figure 5
Novel natural products derived from piezophilic fungi (compound 46).
Figure 6
Figure 6
Novel natural products derived from piezophilic fungi (compounds 47–55). * Absolute configuration is not determined.
Figure 6
Figure 6
Novel natural products derived from piezophilic fungi (compounds 47–55). * Absolute configuration is not determined.
Figure 7
Figure 7
Novel natural products derived from piezophilic fungi (compound 56).
Figure 8
Figure 8
Novel natural products derived from piezophilic fungi (compounds 57–60).
Figure 9
Figure 9
Novel natural products derived from piezophilic fungi (compounds 61–71).
Figure 10
Figure 10
Novel natural products derived from piezophilic fungi (compounds 72–73).
Figure 11
Figure 11
Novel natural products derived from piezophilic fungi (compounds 74–76).
Figure 12
Figure 12
Novel natural products derived from piezophilic fungi (compounds 77–78).
Figure 13
Figure 13
Novel natural products derived from piezophilic fungi (compounds 79–85).
Figure 14
Figure 14
Novel natural products derived from piezophilic fungi (compounds 86–93).
Figure 15
Figure 15
Novel natural products derived from piezophilic fungi (compounds 94–99).
Figure 16
Figure 16
Novel natural products derived from piezophilic fungi (compounds 100–103).
Figure 17
Figure 17
Novel natural products derived from piezophilic fungi (compounds 104–107).
Figure 18
Figure 18
Novel natural products derived from piezophilic fungi (compounds 108–112).
Figure 19
Figure 19
Novel natural products derived from piezophilic fungi (compound 113).
Figure 20
Figure 20
Novel natural products derived from piezophilic fungi (compounds 114–119).
Figure 21
Figure 21
Novel natural products derived from piezophilic fungi (compounds 120–123).
Figure 22
Figure 22
Novel natural products derived from piezophilic fungi (compounds 124–142).
Figure 22
Figure 22
Novel natural products derived from piezophilic fungi (compounds 124–142).
Figure 23
Figure 23
Novel natural products derived from piezophilic fungi (compound 143).
Figure 24
Figure 24
Novel natural products derived from psychrophilic fungi (compound 144).
Figure 25
Figure 25
Novel natural products derived from psychrophilic fungi (compounds 145–157).
Figure 25
Figure 25
Novel natural products derived from psychrophilic fungi (compounds 145–157).
Figure 26
Figure 26
Novel natural products derived from psychrophilic fungi (compounds 158–166).
Figure 27
Figure 27
Novel natural products derived from psychrophilic fungi (compounds 167–173). * Absolute configuration is not determined.
Figure 28
Figure 28
Novel natural products derived from psychrophilic fungi (compounds 174–175).
Figure 29
Figure 29
Novel natural products derived from psychrophilic fungi (compounds 176–185).
Figure 30
Figure 30
Novel natural products derived from psychrophilic fungi (compound 186).
Figure 31
Figure 31
Novel natural products derived from psychrophilic fungi (compounds 187–189).
Figure 32
Figure 32
Novel natural products derived from psychrophilic fungi (compounds 190–197).
Figure 33
Figure 33
Novel natural products derived from psychrophilic fungi (compounds 198–199).
Figure 34
Figure 34
Novel natural products derived from psychrophilic fungi (compounds 200–206).
Figure 35
Figure 35
Novel natural products derived from psychrophilic fungi (compounds 207–208).
Figure 36
Figure 36
Novel natural products derived from psychrophilic fungi (compound 209).
Figure 37
Figure 37
Novel natural products derived from thermophilic fungi (compounds 210–214).
Figure 38
Figure 38
Novel natural products derived from thermophilic fungi (compounds 215–220).
Figure 38
Figure 38
Novel natural products derived from thermophilic fungi (compounds 215–220).
Figure 39
Figure 39
Novel natural products derived from thermophilic fungi (compounds 221–232).
Figure 39
Figure 39
Novel natural products derived from thermophilic fungi (compounds 221–232).
Figure 40
Figure 40
Novel natural products derived from thermophilic fungi (compounds 233–234).
Figure 41
Figure 41
Novel natural products derived from thermophilic fungi (compounds 235–243).
Figure 41
Figure 41
Novel natural products derived from thermophilic fungi (compounds 235–243).
Figure 42
Figure 42
Novel natural products derived from thermophilic fungi (compound 244).
Figure 43
Figure 43
Novel natural products derived from thermophilic fungi (compound 245).
Figure 44
Figure 44
Novel natural products derived from halophilic fungi (compounds 246–262). * Absolute configuration is not determined.
Figure 45
Figure 45
Novel natural products derived from halophilic fungi (compounds 263–264).
Figure 46
Figure 46
Novel natural products derived from halophilic fungi (compounds 265–268).
Figure 47
Figure 47
Novel natural products derived from halophilic fungi (compounds 269–282).
Figure 48
Figure 48
Novel natural products derived from xerophilic fungi (compounds 283–285).
Figure 49
Figure 49
Novel natural products derived from xerophilic fungi (compounds 286–287). * Absolute configuration is not determined.
Figure 50
Figure 50
Novel natural products derived from xerophilic fungi (compounds 288–298). * Absolute configuration is not determined.
Figure 50
Figure 50
Novel natural products derived from xerophilic fungi (compounds 288–298). * Absolute configuration is not determined.
Figure 51
Figure 51
Novel natural products derived from acidophilic or alkaliphilic fungi (compounds 299–314). * Absolute configuration is not determined.
Figure 51
Figure 51
Novel natural products derived from acidophilic or alkaliphilic fungi (compounds 299–314). * Absolute configuration is not determined.
See this image and copyright information in PMC

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