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. 2018 Mar;13(1):5-11.

Ischemic Hepatitis - Intercorrelated Pathology

Andrea Olivia Ciobanu  1 , Leonida Gherasim  1
Affiliations

Ischemic Hepatitis - Intercorrelated Pathology

Andrea Olivia Ciobanu et al. Maedica (Bucur). 2018 Mar.

Abstract

Ischemic hepatitis is an important, yet underdiagnosed pathological condition seen in either cardiology or hepatology clinics or intensive care units. The main causes are severe heart failure, circulatory and septic shock. Close monitoring of biological tests (AST, ALT, LDH) together with hemodynamic parameters (blood pressure, cardiac output and central venous pressure) allow for rapid and accurate diagnosis. Correction of hemodynamic parameters, hypoxemia, hepatic and/or renal dysfunction leads to a more favorable outcome of these patients.

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Figures

FIGURE 1.
FIGURE 1.
Multifactorial etiology of ischemic/hypoxic hepatitis – adapted from Waseem et al (4). HF=heart failure
FIGURE 2.
FIGURE 2.
Pathogenesis of hypoxic hepatopathy – adapted from Birrer et al. (13) CVP=central venous pressure; LVF=left ventricular failure; MAP=mean arterial pressure; PaO2=arterial oxygen pressure; RVF=right ventricular failure. --- -->indirect/secondary effect -->direct/primary effect
See this image and copyright information in PMC

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