Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 1985;70(1):38-42.
doi: 10.1007/BF00389456.

X-linked dominant Charcot-Marie-Tooth disease: suggestion of linkage with a cloned DNA sequence from the proximal Xq

A Gal, J Mücke, H Theile, P F Wieacker, H H Ropers, T F Wienker

X-linked dominant Charcot-Marie-Tooth disease: suggestion of linkage with a cloned DNA sequence from the proximal Xq

A Gal et al. Hum Genet. 1985.

Abstract

A large kindred with the X-linked dominant form of peroneal muscular atrophy (Charcot-Marie-Tooth disease) was analyzed for individual variation in the length of DNA fragments after restriction endonuclease digestion. A systematic search was performed for linkage with a series of cloned single-copy DNA sequences of known regional assignment to the human X chromosome. Close linkage was found with the pDP34 probe (DXYS1 locus, Xq13-q21), suggesting that the gene responsible for the disease is located on the proximal long arm of the X chromosome.

PubMed Disclaimer

Similar articles

See all similar articles

Cited by

See all "Cited by" articles

References

    1. Am J Hum Genet. 1980 May;32(3):314-31 - PubMed
    1. Hum Genet. 1981;58(4):351-7 - PubMed
    1. Hum Hered. 1971;21(6):523-42 - PubMed
    1. Am J Hum Genet. 1984 Mar;36(2):265-76 - PubMed
    1. Am J Hum Genet. 1974 Sep;26(5):588-97 - PubMed

Publication types

LinkOut - more resources