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. 1985;70(1):38-42.
doi: 10.1007/BF00389456.

X-linked dominant Charcot-Marie-Tooth disease: suggestion of linkage with a cloned DNA sequence from the proximal Xq

A Gal, J Mücke, H Theile, P F Wieacker, H H Ropers, T F Wienker

X-linked dominant Charcot-Marie-Tooth disease: suggestion of linkage with a cloned DNA sequence from the proximal Xq

A Gal et al. Hum Genet. 1985.

Abstract

A large kindred with the X-linked dominant form of peroneal muscular atrophy (Charcot-Marie-Tooth disease) was analyzed for individual variation in the length of DNA fragments after restriction endonuclease digestion. A systematic search was performed for linkage with a series of cloned single-copy DNA sequences of known regional assignment to the human X chromosome. Close linkage was found with the pDP34 probe (DXYS1 locus, Xq13-q21), suggesting that the gene responsible for the disease is located on the proximal long arm of the X chromosome.

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References

    1. Am J Hum Genet. 1980 May;32(3):314-31 - PubMed
    1. Hum Genet. 1981;58(4):351-7 - PubMed
    1. Hum Hered. 1971;21(6):523-42 - PubMed
    1. Am J Hum Genet. 1984 Mar;36(2):265-76 - PubMed
    1. Am J Hum Genet. 1974 Sep;26(5):588-97 - PubMed

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