Building Capacity for a Global Genome Editing Observatory: Conceptual Challenges

J Benjamin Hurlbut¹, Sheila Jasanoff², Krishanu Saha³, Aziza Ahmed⁴, Anthony Appiah⁵, Elizabeth Bartholet⁶, Françoise Baylis⁷, Gaymon Bennett⁸, George Church⁹, I Glenn Cohen¹⁰, George Daley¹¹, Kevin Finneran¹², William Hurlbut¹³, Rudolf Jaenisch¹⁴, Laurence Lwoff¹⁵, John Paul Kimes¹⁶, Peter Mills¹⁷, Jacob Moses¹⁸, Buhm Soon Park¹⁹, Erik Parens²⁰, Rachel Salzman²¹, Abha Saxena²², Hilton Simmet²³, Tania Simoncelli²⁴, O Carter Snead²⁵, Kaushik Sunder Rajan²⁶, Robert D Truog²⁷, Patricia Williams²⁸, Christiane Woopen²⁹

Affiliations

¹ Arizona State University, Tempe, AZ, USA; Note: The views expressed in this article are those of the authors and do not represent the official policies or positions of the organizations with which they are affiliated. Author affiliations are as of April, 2017. Electronic address: bhurlbut@asu.edu.
² Harvard Kennedy School, Cambridge, MA, USA; Website: http://sts.hks.harvard.edu/. Electronic address: sheila_jasanoff@harvard.edu.
³ University of Wisconsin-Madison, Madison, WI, USA; Website: https://sahalab.bme.wisc.edu/. Electronic address: ksaha@wisc.edu.
⁴ Northeastern University School of Law, Boston, MA, USA. Electronic address: http://twitter.com/@AzizaAhmed.
⁵ New York University, New York, NY, USA. Electronic address: http://twitter.com/@KAnthonyAppiah.
⁶ Harvard Law School, Cambridge, MA, USA.
⁷ Dalhousie University, Halifax, Nova Scotia, Canada. Electronic address: http://twitter.com/@FrancoiseBaylis.
⁸ Arizona State University, Tempe, AZ, USA.
⁹ Harvard Medical School, Boston, MA, USA. Electronic address: http://twitter.com/@geochurch.
¹⁰ Harvard Law School, Cambridge, MA, USA. Electronic address: http://twitter.com/@CohenProf.
¹¹ Harvard Medical School, Boston, MA, USA. Electronic address: http://twitter.com/@G_Q_Daley.
¹² National Academies of Science, Engineering and Medicine, Washington, DC, USA.
¹³ Stanford University School of Medicine, Stanford, CA, USA.
¹⁴ Whitehead Institute for Biomedical Research, Cambridge, MA, USA; Massachusetts Institute of Technology, Cambridge, MA, USA.
¹⁵ Council of Europe, Strasbourg, France.
¹⁶ University of Notre Dame, Notre Dame, IN, USA.
¹⁷ Nuffield Council on Bioethics, London, UK. Electronic address: http://twitter.com/@PeterFRMills.
¹⁸ Harvard University, Cambridge, MA, USA.
¹⁹ Korea Advanced Institute of Science & Technology, Daejeon, South Korea.
²⁰ The Hastings Center, Garrison, NY, USA.
²¹ ALD Connect, Boston, MA, USA.
²² World Health Organization, Geneva, Switzerland.
²³ Harvard Kennedy School, Cambridge, MA, USA.
²⁴ Broad Institute, Cambridge, MA, USA.
²⁵ University of Notre Dame, Law School, Notre Dame, IN, USA. Electronic address: http://twitter.com/@cartersnead.
²⁶ University of Chicago, Chicago, IL, USA.
²⁷ Harvard Law School, Cambridge, MA, USA; Boston Children's Hospital, Boston, MA, USA.
²⁸ Columbia Law School, New York, NY, USA.
²⁹ Research Unit Ethics and CERES, University of Cologne, Köln, Germany. Electronic address: http://twitter.com/@CWoopen.

PMID: 29871776
PMCID: PMC6573010
DOI: 10.1016/j.tibtech.2018.04.009

Building Capacity for a Global Genome Editing Observatory: Conceptual Challenges

J Benjamin Hurlbut et al. Trends Biotechnol. 2018 Jul.

. 2018 Jul;36(7):639-641.

doi: 10.1016/j.tibtech.2018.04.009. Epub 2018 Jun 2.

Authors

Affiliations

¹ Arizona State University, Tempe, AZ, USA; Note: The views expressed in this article are those of the authors and do not represent the official policies or positions of the organizations with which they are affiliated. Author affiliations are as of April, 2017. Electronic address: bhurlbut@asu.edu.
² Harvard Kennedy School, Cambridge, MA, USA; Website: http://sts.hks.harvard.edu/. Electronic address: sheila_jasanoff@harvard.edu.
³ University of Wisconsin-Madison, Madison, WI, USA; Website: https://sahalab.bme.wisc.edu/. Electronic address: ksaha@wisc.edu.
⁴ Northeastern University School of Law, Boston, MA, USA. Electronic address: http://twitter.com/@AzizaAhmed.
⁵ New York University, New York, NY, USA. Electronic address: http://twitter.com/@KAnthonyAppiah.
⁶ Harvard Law School, Cambridge, MA, USA.
⁷ Dalhousie University, Halifax, Nova Scotia, Canada. Electronic address: http://twitter.com/@FrancoiseBaylis.
⁸ Arizona State University, Tempe, AZ, USA.
⁹ Harvard Medical School, Boston, MA, USA. Electronic address: http://twitter.com/@geochurch.
¹⁰ Harvard Law School, Cambridge, MA, USA. Electronic address: http://twitter.com/@CohenProf.
¹¹ Harvard Medical School, Boston, MA, USA. Electronic address: http://twitter.com/@G_Q_Daley.
¹² National Academies of Science, Engineering and Medicine, Washington, DC, USA.
¹³ Stanford University School of Medicine, Stanford, CA, USA.
¹⁴ Whitehead Institute for Biomedical Research, Cambridge, MA, USA; Massachusetts Institute of Technology, Cambridge, MA, USA.
¹⁵ Council of Europe, Strasbourg, France.
¹⁶ University of Notre Dame, Notre Dame, IN, USA.
¹⁷ Nuffield Council on Bioethics, London, UK. Electronic address: http://twitter.com/@PeterFRMills.
¹⁸ Harvard University, Cambridge, MA, USA.
¹⁹ Korea Advanced Institute of Science & Technology, Daejeon, South Korea.
²⁰ The Hastings Center, Garrison, NY, USA.
²¹ ALD Connect, Boston, MA, USA.
²² World Health Organization, Geneva, Switzerland.
²³ Harvard Kennedy School, Cambridge, MA, USA.
²⁴ Broad Institute, Cambridge, MA, USA.
²⁵ University of Notre Dame, Law School, Notre Dame, IN, USA. Electronic address: http://twitter.com/@cartersnead.
²⁶ University of Chicago, Chicago, IL, USA.
²⁷ Harvard Law School, Cambridge, MA, USA; Boston Children's Hospital, Boston, MA, USA.
²⁸ Columbia Law School, New York, NY, USA.
²⁹ Research Unit Ethics and CERES, University of Cologne, Köln, Germany. Electronic address: http://twitter.com/@CWoopen.

PMID: 29871776
PMCID: PMC6573010
DOI: 10.1016/j.tibtech.2018.04.009

Abstract

A new infrastructure is urgently needed at the global level to facilitate exchange on key issues concerning genome editing. We advocate the establishment of a global observatory to serve as a center for international, interdisciplinary, and cosmopolitan reflection. This article is the first of a two-part series.

Keywords: CRISPR; bioethics; ethics; gene editing; science and technology studies; science policy.

PubMed Disclaimer

References

1. Jasanoff S, and Hurlbut JB. “A global observatory for gene editing.” Nature 555, no. 7697 (2018): 435. - PubMed
1. Doudna Jennifer A., and Sternberg Samuel H.. (2017) A Crack in Creation: Gene Editing and the Unthinkable Power to Control Evolution. Houghton Mifflin Harcourt.
1. International Summit on Human Gene Editing: A Global Discussion. (2015) http://www8.nationalacademies.org/onpinews/newsitem.aspx?RecordID=12032015a - PubMed
1. Pei D, Beier DW, Levy-Lahad E, Marchant G, Rossant J, Izpisua Belmonte JC, Lovell-Badge R, Jaenisch R, Charo A, and Baltimore D (2017) Cell Stem Cell 21, 423–426. - PubMed
1. Germany: (2014, last amended) Basic Law for the Federal Republic of Germany. https://www.btg-bestellservice.de/pdf/80201000.pdf

Publication types

Actions
Actions
Actions

MeSH terms

Actions
Actions
Actions
Actions

Grants and funding

LinkOut - more resources

Full Text Sources
Other Literature Sources
- scite Smart Citations

Save citation to file

Email citation

Add to Collections

Add to My Bibliography

Your saved search

Create a file for external citation management software

Your RSS Feed

Building Capacity for a Global Genome Editing Observatory: Conceptual Challenges

Affiliations

Building Capacity for a Global Genome Editing Observatory: Conceptual Challenges

Authors

Affiliations

Abstract

References

Publication types

MeSH terms

Grants and funding

LinkOut - more resources

Full Text Sources

Other Literature Sources