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. 1985 Jun;162(3):1317-9.
doi: 10.1128/jb.162.3.1317-1319.1985.

Restriction endonuclease analysis of the ilvGEDA operon of members of the family Enterobacteriaceae

R P Driver, R P Lawther

Restriction endonuclease analysis of the ilvGEDA operon of members of the family Enterobacteriaceae

R P Driver et al. J Bacteriol. 1985 Jun.

Abstract

Four of the genes required for the biosynthesis of isoleucine and valine form the ilvGEDA operon in Escherichia coli K-12 and Salmonella typhimurium. The structural relationship of these genes was examined in eight other members of the family Enterobacteriaceae by genomic Southern blot hybridization. These genes are contiguous in all the strains examined, and specific restriction sites appear to be highly conserved, indicating the possible functional importance of the DNA sequences of which they are part.

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